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• W2135604144 abstract "The antitumoral activity of a series of acetylated bis-tetrahydrofuranic acetogenins with a threo/trans/threo/trans/erythro relative configuration was characterized by four new natural and two semisynthetic, 15,24,30-trioxygenated acetogenins that were found to inhibit mitochondrial complex I enzyme as well as growth of several tumor cell lines. Placement of acetyl groups along the alkyl chain modulated the potency of the bis-tetrahydrofuranic acetogenins and could be important for future utilization of these compounds as chemotherapeutic agents." @default.
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• W2135604144 date "2006-02-01" @default.
• W2135604144 modified "2023-10-18" @default.
• W2135604144 title "Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors" @default.
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• W2135604144 doi "https://doi.org/10.1016/j.bmc.2005.09.036" @default.
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