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- W2135649969 abstract "Admixture mapping is a disease-mapping strategy to identify disease susceptibility variants in an admixed population that is a result of mating between 2 historically separated populations differing in allele frequencies and disease prevalence. With the increasing availability of high-density genotyping data generated in genome-wide association studies, it is of interest to investigate how to apply admixture mapping in the context of the genome-wide association studies and how to adjust for admixture in association tests. In this study, we first evaluated 3 different local ancestry inference methods, LAMP, LAMP-LD, and MULTIMIX. Then we applied admixture mapping analysis based on estimated local ancestry. Finally, we performed association tests with adjustment for local ancestry." @default.
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- W2135649969 date "2014-06-01" @default.
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- W2135649969 title "Admixture mapping analysis in the context of GWAS with GAW18 data" @default.
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- W2135649969 doi "https://doi.org/10.1186/1753-6561-8-s1-s3" @default.
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