FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135652528> ?p ?o ?g. }

• W2135652528 endingPage "1145" @default.
• W2135652528 startingPage "1138" @default.
• W2135652528 abstract "Infusion of triglycerides and heparin causes insulin resistance in muscle. Because the vascular actions of insulin, particularly capillary recruitment, may contribute to the increase in glucose uptake by skeletal muscle, we investigated the effects of Intralipid/heparin infusion on the hemodynamic actions of insulin during clamp conditions. Saline or 10% Intralipid/heparin (33 U/ml) was infused into anesthetized rats at 20 microl/min for 6 h. At 4 h into the saline infusion, a 2-h hyperinsulinemic (3 mU. min(-1).kg(-1))-euglycemic clamp was conducted (Ins group). At 4 h into the lipid infusion, a 2-h saline control (Lip group) or 2-h hyperinsulinemic-euglycemic clamp (Lip + Ins group) was conducted. Arterial blood pressure, heart rate, femoral blood flow (FBF), hindleg vascular resistance, glucose infusion rate (GIR), hindleg glucose uptake (HGU), and muscle 2-deoxyglucose uptake (R'g) were measured. Capillary recruitment, as measured by metabolism of infused 1-methylxanthine (1-MX), was also assessed. When compared with either Lip or Lip + Ins, Ins had no effect on arterial blood pressure, heart rate, FBF, or vascular resistance but increased GIR, HGU, and R'g of soleus, plantaris, extensor digitorum longus, and gastrocnemius red muscles and hindlimb 1-MX metabolism. GIR, HGU, and R'g of soleus, plantaris, gastrocnemius red, and the combined muscles and 1-MX metabolism were less in Lip + Ins than in Ins rats. HGU correlated closely with hindleg capillary recruitment (r = 0.86, P < 0.001) but not total hindleg blood flow. In conclusion, acute elevation of plasma free fatty acids blocks insulin-mediated glucose uptake and capillary recruitment." @default.
• W2135652528 created "2016-06-24" @default.
• W2135652528 creator A5003272299 @default.
• W2135652528 creator A5032479781 @default.
• W2135652528 creator A5033285682 @default.
• W2135652528 date "2002-04-01" @default.
• W2135652528 modified "2023-10-17" @default.
• W2135652528 title "Lipid Infusion Impairs Physiologic Insulin-Mediated Capillary Recruitment and Muscle Glucose Uptake In Vivo" @default.
• W2135652528 cites W1782741946 @default.
• W2135652528 cites W1959312622 @default.
• W2135652528 cites W1966755400 @default.
• W2135652528 cites W1969894012 @default.
• W2135652528 cites W1970923910 @default.
• W2135652528 cites W1975200587 @default.
• W2135652528 cites W1975282746 @default.
• W2135652528 cites W1975856100 @default.
• W2135652528 cites W1990509911 @default.
• W2135652528 cites W1991795789 @default.
• W2135652528 cites W1992527366 @default.
• W2135652528 cites W1993480864 @default.
• W2135652528 cites W2003755391 @default.
• W2135652528 cites W2007856467 @default.
• W2135652528 cites W2008793522 @default.
• W2135652528 cites W2012898950 @default.
• W2135652528 cites W2016070194 @default.
• W2135652528 cites W2022249257 @default.
• W2135652528 cites W2023323317 @default.
• W2135652528 cites W2031888891 @default.
• W2135652528 cites W2033125833 @default.
• W2135652528 cites W2036515253 @default.
• W2135652528 cites W2043106623 @default.
• W2135652528 cites W2044179508 @default.
• W2135652528 cites W2047284900 @default.
• W2135652528 cites W2059842910 @default.
• W2135652528 cites W2075408008 @default.
• W2135652528 cites W2086785365 @default.
• W2135652528 cites W2099914905 @default.
• W2135652528 cites W2113395866 @default.
• W2135652528 cites W2115830695 @default.
• W2135652528 cites W2120210721 @default.
• W2135652528 cites W2125969338 @default.
• W2135652528 cites W2126030103 @default.
• W2135652528 cites W2126171305 @default.
• W2135652528 cites W2130200187 @default.
• W2135652528 cites W2136566554 @default.
• W2135652528 cites W2138700089 @default.
• W2135652528 cites W2142639539 @default.
• W2135652528 cites W2143789428 @default.
• W2135652528 cites W2146877877 @default.
• W2135652528 cites W2147332678 @default.
• W2135652528 cites W2148176455 @default.
• W2135652528 cites W2155465717 @default.
• W2135652528 cites W2184256477 @default.
• W2135652528 cites W219485921 @default.
• W2135652528 cites W2202075382 @default.
• W2135652528 cites W2225395848 @default.
• W2135652528 cites W2243792270 @default.
• W2135652528 cites W2337553235 @default.
• W2135652528 cites W2342318206 @default.
• W2135652528 cites W336175586 @default.
• W2135652528 cites W4248020807 @default.
• W2135652528 cites W4248064242 @default.
• W2135652528 cites W4251495841 @default.
• W2135652528 cites W4254077102 @default.
• W2135652528 doi "https://doi.org/10.2337/diabetes.51.4.1138" @default.
• W2135652528 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11916937" @default.
• W2135652528 hasPublicationYear "2002" @default.
• W2135652528 type Work @default.
• W2135652528 sameAs 2135652528 @default.
• W2135652528 citedByCount "156" @default.
• W2135652528 countsByYear W21356525282012 @default.
• W2135652528 countsByYear W21356525282013 @default.
• W2135652528 countsByYear W21356525282014 @default.
• W2135652528 countsByYear W21356525282015 @default.
• W2135652528 countsByYear W21356525282016 @default.
• W2135652528 countsByYear W21356525282017 @default.
• W2135652528 countsByYear W21356525282018 @default.
• W2135652528 countsByYear W21356525282019 @default.
• W2135652528 countsByYear W21356525282020 @default.
• W2135652528 countsByYear W21356525282021 @default.
• W2135652528 countsByYear W21356525282022 @default.
• W2135652528 countsByYear W21356525282023 @default.
• W2135652528 crossrefType "journal-article" @default.
• W2135652528 hasAuthorship W2135652528A5003272299 @default.
• W2135652528 hasAuthorship W2135652528A5032479781 @default.
• W2135652528 hasAuthorship W2135652528A5033285682 @default.
• W2135652528 hasBestOaLocation W21356525281 @default.
• W2135652528 hasConcept C126322002 @default.
• W2135652528 hasConcept C134018914 @default.
• W2135652528 hasConcept C17093226 @default.
• W2135652528 hasConcept C178853913 @default.
• W2135652528 hasConcept C2775872116 @default.
• W2135652528 hasConcept C2777391703 @default.
• W2135652528 hasConcept C2777397205 @default.
• W2135652528 hasConcept C2777866211 @default.
• W2135652528 hasConcept C2778808658 @default.
• W2135652528 hasConcept C2779306644 @default.
• W2135652528 hasConcept C2779959927 @default.

• next