FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135654340> ?p ?o ?g. }

• W2135654340 endingPage "92" @default.
• W2135654340 startingPage "88" @default.
• W2135654340 abstract "Although numerous clinical trials have evaluated the body weight change achieved using diabetes medications alone or in combinations, the composition of body weight change in these clinical trials has rarely been assessed. We aimed to evaluate the effects of gliclazide, metformin, and acarbose monotherapy on body composition, fat distribution, and other cardiometabolic risk factors in patients with newly diagnosed type 2 diabetes. A total of 86 patients with newly diagnosed type 2 diabetes mellitus were randomly assigned to receive gliclazide, metformin, or acarbose for 6 months. Dual-energy x-ray absorptiometry; abdominal computed tomography scans; and measurements of adiponectin, leptin, and lipid levels were performed before and after 6-month monodrug therapy. Blood glucose and glycosylated hemoglobin levels significantly improved after 6 months of monodrug therapy. During the 6 months of use of the 3 antidiabetes medications, the majority of participants experienced fat mass loss and lean mass gain. Metformin monotherapy in patients with newly diagnosed type 2 diabetes led to a significant decrease in percent body fat (P = 0.029) and body fat mass (P = 0.038). Levels of serum total cholesterol (P = 0.004), triglycerides (P = 0.014), and adiponectin (P = 0.001) took a favorable turn after metformin treatment. The 3 antidiabetes medications caused no significant change in abdominal fat distribution, waist circumstance, and blood pressure during the 6 months. Our results suggest metformin therapy in patients with newly diagnosed type 2 diabetes can improve cardiometabolic risk markers. Moreover, body composition change induced by gliclazide and acarbose was not likely to be simple fat deposition." @default.
• W2135654340 created "2016-06-24" @default.
• W2135654340 creator A5013528584 @default.
• W2135654340 creator A5025384599 @default.
• W2135654340 creator A5049081910 @default.
• W2135654340 creator A5060519673 @default.
• W2135654340 creator A5070133967 @default.
• W2135654340 creator A5087359356 @default.
• W2135654340 date "2013-12-01" @default.
• W2135654340 modified "2023-10-16" @default.
• W2135654340 title "The Effects of Gliclazide, Metformin, and Acarbose on Body Composition in Patients with Newly Diagnosed Type 2 Diabetes Mellitus" @default.
• W2135654340 cites W1980616406 @default.
• W2135654340 cites W1983084864 @default.
• W2135654340 cites W1992610640 @default.
• W2135654340 cites W1996221805 @default.
• W2135654340 cites W2007687205 @default.
• W2135654340 cites W2010239915 @default.
• W2135654340 cites W2026835770 @default.
• W2135654340 cites W2068394230 @default.
• W2135654340 cites W2069661907 @default.
• W2135654340 cites W2082037132 @default.
• W2135654340 cites W2088573595 @default.
• W2135654340 cites W2097052470 @default.
• W2135654340 cites W2122686769 @default.
• W2135654340 cites W2131343538 @default.
• W2135654340 cites W2138781309 @default.
• W2135654340 cites W2152870560 @default.
• W2135654340 cites W2154485641 @default.
• W2135654340 cites W2160921359 @default.
• W2135654340 cites W2171440185 @default.
• W2135654340 doi "https://doi.org/10.1016/j.curtheres.2013.10.002" @default.
• W2135654340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3898190" @default.
• W2135654340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24465050" @default.
• W2135654340 hasPublicationYear "2013" @default.
• W2135654340 type Work @default.
• W2135654340 sameAs 2135654340 @default.
• W2135654340 citedByCount "34" @default.
• W2135654340 countsByYear W21356543402014 @default.
• W2135654340 countsByYear W21356543402015 @default.
• W2135654340 countsByYear W21356543402016 @default.
• W2135654340 countsByYear W21356543402018 @default.
• W2135654340 countsByYear W21356543402019 @default.
• W2135654340 countsByYear W21356543402020 @default.
• W2135654340 countsByYear W21356543402021 @default.
• W2135654340 countsByYear W21356543402022 @default.
• W2135654340 countsByYear W21356543402023 @default.
• W2135654340 crossrefType "journal-article" @default.
• W2135654340 hasAuthorship W2135654340A5013528584 @default.
• W2135654340 hasAuthorship W2135654340A5025384599 @default.
• W2135654340 hasAuthorship W2135654340A5049081910 @default.
• W2135654340 hasAuthorship W2135654340A5060519673 @default.
• W2135654340 hasAuthorship W2135654340A5070133967 @default.
• W2135654340 hasAuthorship W2135654340A5087359356 @default.
• W2135654340 hasBestOaLocation W21356543401 @default.
• W2135654340 hasConcept C126322002 @default.
• W2135654340 hasConcept C134018914 @default.
• W2135654340 hasConcept C2776193436 @default.
• W2135654340 hasConcept C2776617576 @default.
• W2135654340 hasConcept C2776782570 @default.
• W2135654340 hasConcept C2777180221 @default.
• W2135654340 hasConcept C2777391703 @default.
• W2135654340 hasConcept C2777448766 @default.
• W2135654340 hasConcept C2780221984 @default.
• W2135654340 hasConcept C2780323712 @default.
• W2135654340 hasConcept C2910068830 @default.
• W2135654340 hasConcept C555293320 @default.
• W2135654340 hasConcept C71924100 @default.
• W2135654340 hasConcept C90924648 @default.
• W2135654340 hasConceptScore W2135654340C126322002 @default.
• W2135654340 hasConceptScore W2135654340C134018914 @default.
• W2135654340 hasConceptScore W2135654340C2776193436 @default.
• W2135654340 hasConceptScore W2135654340C2776617576 @default.
• W2135654340 hasConceptScore W2135654340C2776782570 @default.
• W2135654340 hasConceptScore W2135654340C2777180221 @default.
• W2135654340 hasConceptScore W2135654340C2777391703 @default.
• W2135654340 hasConceptScore W2135654340C2777448766 @default.
• W2135654340 hasConceptScore W2135654340C2780221984 @default.
• W2135654340 hasConceptScore W2135654340C2780323712 @default.
• W2135654340 hasConceptScore W2135654340C2910068830 @default.
• W2135654340 hasConceptScore W2135654340C555293320 @default.
• W2135654340 hasConceptScore W2135654340C71924100 @default.
• W2135654340 hasConceptScore W2135654340C90924648 @default.
• W2135654340 hasLocation W21356543401 @default.
• W2135654340 hasLocation W21356543402 @default.
• W2135654340 hasLocation W21356543403 @default.
• W2135654340 hasLocation W21356543404 @default.
• W2135654340 hasOpenAccess W2135654340 @default.
• W2135654340 hasPrimaryLocation W21356543401 @default.
• W2135654340 hasRelatedWork W1974802955 @default.
• W2135654340 hasRelatedWork W1988439151 @default.
• W2135654340 hasRelatedWork W2035107691 @default.
• W2135654340 hasRelatedWork W2059941456 @default.
• W2135654340 hasRelatedWork W2102820875 @default.
• W2135654340 hasRelatedWork W221229666 @default.
• W2135654340 hasRelatedWork W2360290027 @default.
• W2135654340 hasRelatedWork W2375944679 @default.
• W2135654340 hasRelatedWork W2390031915 @default.
• W2135654340 hasRelatedWork W2461275335 @default.

• next