FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135657957> ?p ?o ?g. }

• W2135657957 endingPage "1009S" @default.
• W2135657957 startingPage "989S" @default.
• W2135657957 abstract "Human studies provide evidence for beneficial effects of polyphenol-rich foods on cardiovascular health. The antioxidant activity of polyphenols potentially explains these effects, but is the antioxidant activity a reliable predictor for these effects? An International Life Sciences Institute Europe working group addressed this question and explored the potential of antioxidant claims for polyphenols in relation to cardiovascular health by using the so-called Process for the Assessment of Scientific Support for Claims on Foods project criteria. In this process, analytical aspects of polyphenols, their occurrence in foods, dietary intake, and bioavailability were reviewed. Human studies on polyphenols and cardiovascular health were reviewed together with methods for biomarkers of oxidative damage and total antioxidant capacity (TAC). In retrospective studies, F2-isoprostanes and oxidized LDL, the most reliable biomarkers of lipid peroxidation, and measures for TAC showed the expected differences between cardiovascular disease patients and healthy controls, but prospective studies are lacking, and a causal relationship between these biomarkers and cardiovascular health could not be established. Therefore, the physiological relevance of a potential change in these biomarkers is unclear. We found limited evidence that some types of polyphenol-rich products modify these biomarkers in humans. A direct antioxidant effect of polyphenols in vivo is questionable, however, because concentrations in blood are low compared with other antioxidants and extensive metabolism following ingestion lowers their antioxidant activity. Therefore, the biological relevance of direct antioxidant effects of polyphenols for cardiovascular health could not be established. Overall, although some polyphenol-rich foods exert beneficial effects on some biomarkers of cardiovascular health, there is no evidence that this is caused by improvements in antioxidant function biomarkers (oxidative damage or antioxidant capacity)." @default.
• W2135657957 created "2016-06-24" @default.
• W2135657957 creator A5000353299 @default.
• W2135657957 creator A5005097979 @default.
• W2135657957 creator A5005317096 @default.
• W2135657957 creator A5009288503 @default.
• W2135657957 creator A5021449136 @default.
• W2135657957 creator A5032820729 @default.
• W2135657957 creator A5050752543 @default.
• W2135657957 creator A5056572381 @default.
• W2135657957 creator A5068877163 @default.
• W2135657957 creator A5090984354 @default.
• W2135657957 date "2011-05-01" @default.
• W2135657957 modified "2023-10-12" @default.
• W2135657957 title "The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4" @default.
• W2135657957 cites W1020919336 @default.
• W2135657957 cites W119916385 @default.
• W2135657957 cites W1541783084 @default.
• W2135657957 cites W1607459610 @default.
• W2135657957 cites W1614231230 @default.
• W2135657957 cites W1745529008 @default.
• W2135657957 cites W1828830668 @default.
• W2135657957 cites W1864172753 @default.
• W2135657957 cites W1865530734 @default.
• W2135657957 cites W1876665543 @default.
• W2135657957 cites W1890181225 @default.
• W2135657957 cites W1891638778 @default.
• W2135657957 cites W1895964898 @default.
• W2135657957 cites W1904908546 @default.
• W2135657957 cites W1912228249 @default.
• W2135657957 cites W1914843938 @default.
• W2135657957 cites W1932498841 @default.
• W2135657957 cites W1933201474 @default.
• W2135657957 cites W1944481812 @default.
• W2135657957 cites W1946815265 @default.
• W2135657957 cites W1948619662 @default.
• W2135657957 cites W1953209992 @default.
• W2135657957 cites W1953353401 @default.
• W2135657957 cites W1955371799 @default.
• W2135657957 cites W1966078997 @default.
• W2135657957 cites W1967265923 @default.
• W2135657957 cites W1967678385 @default.
• W2135657957 cites W1967817279 @default.
• W2135657957 cites W1972060131 @default.
• W2135657957 cites W1974872215 @default.
• W2135657957 cites W1976616659 @default.
• W2135657957 cites W1976737243 @default.
• W2135657957 cites W1978847420 @default.
• W2135657957 cites W1979835159 @default.
• W2135657957 cites W1982059829 @default.
• W2135657957 cites W1983079790 @default.
• W2135657957 cites W1984048346 @default.
• W2135657957 cites W1984334990 @default.
• W2135657957 cites W1986366688 @default.
• W2135657957 cites W1987415708 @default.
• W2135657957 cites W1988346971 @default.
• W2135657957 cites W1988505553 @default.
• W2135657957 cites W1988675268 @default.
• W2135657957 cites W1991091713 @default.
• W2135657957 cites W1992032130 @default.
• W2135657957 cites W1993083361 @default.
• W2135657957 cites W1993210215 @default.
• W2135657957 cites W1993966022 @default.
• W2135657957 cites W1994227902 @default.
• W2135657957 cites W1994604269 @default.
• W2135657957 cites W1994931665 @default.
• W2135657957 cites W1995266484 @default.
• W2135657957 cites W1995549107 @default.
• W2135657957 cites W1996370937 @default.
• W2135657957 cites W1996797317 @default.
• W2135657957 cites W1996922652 @default.
• W2135657957 cites W1997907701 @default.
• W2135657957 cites W1998394852 @default.
• W2135657957 cites W1998466474 @default.
• W2135657957 cites W1998503377 @default.
• W2135657957 cites W1998936301 @default.
• W2135657957 cites W2001110632 @default.
• W2135657957 cites W2001641852 @default.
• W2135657957 cites W2004173507 @default.
• W2135657957 cites W2005329948 @default.
• W2135657957 cites W2006492339 @default.
• W2135657957 cites W2007467101 @default.
• W2135657957 cites W2009018570 @default.
• W2135657957 cites W2009574832 @default.
• W2135657957 cites W2010173489 @default.
• W2135657957 cites W2012525268 @default.
• W2135657957 cites W2013292119 @default.
• W2135657957 cites W2016503982 @default.
• W2135657957 cites W2020085674 @default.
• W2135657957 cites W2021010648 @default.
• W2135657957 cites W2021470699 @default.
• W2135657957 cites W2023677185 @default.
• W2135657957 cites W2025599495 @default.
• W2135657957 cites W2026270872 @default.
• W2135657957 cites W2026905117 @default.
• W2135657957 cites W2027836418 @default.
• W2135657957 cites W2028816863 @default.
• W2135657957 cites W2029456271 @default.

• next