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• W2135683315 abstract "A double-isotope derivative dilution procedure for measuring plasma levels of Nortriptyline is described. The assay is specific, sensitive, precise and reproducible. Studies on the variation in steady-state plasma levels are described on a fixed oral dosage of nortriptyline. Between individual variations in steady-state plasma levels are large. Between day within individual variation is 15–20%. Dosage regime, time of blood sampling after hist oral dose and the method of blood handling are unlikely to affect the steady-state plasma levels. Within an individual, the oral dose, duration of treatment and concomitant drug treatment are all important determinants of the steady-state plasma level." @default.
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• W2135683315 date "1976-03-01" @default.
• W2135683315 modified "2023-09-25" @default.
• W2135683315 title "The Measurement of Plasma Levels of Tricyclic Antidepressant Drugs" @default.
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• W2135683315 doi "https://doi.org/10.3109/00048677609159479" @default.
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