Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135756073> ?p ?o ?g. }
- W2135756073 abstract "Targeted delivery of drugs and sensors into cells is an attractive technology with both medical and scientific applications. Existing delivery vehicles are generally limited by the complexity of their design, dependence on active transport and inability to function within cellular compartments. Here, we developed self-assembled nanofibrous hydrogel fibers using a biologically inert, low-molecular-weight amphiphile. Self-assembled nanofibrous hydrogels offer unique physical/mechanical properties and can easily be loaded with a diverse range of payloads. Unlike commercially available E. coli membrane particles covalently bound to the pH reporting dye pHrodo, pHrodo encapsulated in self-assembled hydrogel-fibers internalizes into macrophages at both physiologic (37°C) and sub-physiologic (4°C) temperatures through an energy-independent, passive process. Unlike dye alone or pHrodo complexed to E. coli, pHrodo-SAFs report pH in both the cytoplasm and phagosomes, as well the nucleus. This new class of materials should be useful for next-generation sensing of the intracellular milieu." @default.
- W2135756073 created "2016-06-24" @default.
- W2135756073 creator A5005819559 @default.
- W2135756073 creator A5022052017 @default.
- W2135756073 creator A5022397973 @default.
- W2135756073 creator A5042223305 @default.
- W2135756073 creator A5044348796 @default.
- W2135756073 creator A5057978103 @default.
- W2135756073 creator A5065691680 @default.
- W2135756073 creator A5066638992 @default.
- W2135756073 creator A5070789294 @default.
- W2135756073 creator A5077722317 @default.
- W2135756073 date "2014-03-26" @default.
- W2135756073 modified "2023-09-30" @default.
- W2135756073 title "Self-assembled hydrogel fibers for sensing the multi-compartment intracellular milieu" @default.
- W2135756073 cites W1484446060 @default.
- W2135756073 cites W1900660557 @default.
- W2135756073 cites W1934439616 @default.
- W2135756073 cites W1978059664 @default.
- W2135756073 cites W1989797453 @default.
- W2135756073 cites W1991660232 @default.
- W2135756073 cites W1993373375 @default.
- W2135756073 cites W2001389730 @default.
- W2135756073 cites W2002047195 @default.
- W2135756073 cites W2003110090 @default.
- W2135756073 cites W2013498013 @default.
- W2135756073 cites W2015497529 @default.
- W2135756073 cites W2016790205 @default.
- W2135756073 cites W2024269331 @default.
- W2135756073 cites W2025824197 @default.
- W2135756073 cites W2036312601 @default.
- W2135756073 cites W2037122021 @default.
- W2135756073 cites W2041136418 @default.
- W2135756073 cites W2043554487 @default.
- W2135756073 cites W2044708260 @default.
- W2135756073 cites W2052527966 @default.
- W2135756073 cites W2057463855 @default.
- W2135756073 cites W2066834294 @default.
- W2135756073 cites W2067901617 @default.
- W2135756073 cites W2085943635 @default.
- W2135756073 cites W2092475403 @default.
- W2135756073 cites W2100326315 @default.
- W2135756073 cites W2124021158 @default.
- W2135756073 cites W2136000113 @default.
- W2135756073 cites W2138094116 @default.
- W2135756073 cites W2161085595 @default.
- W2135756073 cites W2163573140 @default.
- W2135756073 cites W2168469435 @default.
- W2135756073 cites W2171439027 @default.
- W2135756073 cites W2313880422 @default.
- W2135756073 cites W2323929392 @default.
- W2135756073 cites W2415068028 @default.
- W2135756073 cites W4233744513 @default.
- W2135756073 cites W5129184 @default.
- W2135756073 doi "https://doi.org/10.1038/srep04466" @default.
- W2135756073 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3966031" @default.
- W2135756073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24667734" @default.
- W2135756073 hasPublicationYear "2014" @default.
- W2135756073 type Work @default.
- W2135756073 sameAs 2135756073 @default.
- W2135756073 citedByCount "18" @default.
- W2135756073 countsByYear W21357560732014 @default.
- W2135756073 countsByYear W21357560732015 @default.
- W2135756073 countsByYear W21357560732016 @default.
- W2135756073 countsByYear W21357560732017 @default.
- W2135756073 countsByYear W21357560732018 @default.
- W2135756073 countsByYear W21357560732019 @default.
- W2135756073 countsByYear W21357560732020 @default.
- W2135756073 crossrefType "journal-article" @default.
- W2135756073 hasAuthorship W2135756073A5005819559 @default.
- W2135756073 hasAuthorship W2135756073A5022052017 @default.
- W2135756073 hasAuthorship W2135756073A5022397973 @default.
- W2135756073 hasAuthorship W2135756073A5042223305 @default.
- W2135756073 hasAuthorship W2135756073A5044348796 @default.
- W2135756073 hasAuthorship W2135756073A5057978103 @default.
- W2135756073 hasAuthorship W2135756073A5065691680 @default.
- W2135756073 hasAuthorship W2135756073A5066638992 @default.
- W2135756073 hasAuthorship W2135756073A5070789294 @default.
- W2135756073 hasAuthorship W2135756073A5077722317 @default.
- W2135756073 hasBestOaLocation W21357560731 @default.
- W2135756073 hasConcept C108586683 @default.
- W2135756073 hasConcept C12554922 @default.
- W2135756073 hasConcept C15920480 @default.
- W2135756073 hasConcept C161478664 @default.
- W2135756073 hasConcept C171250308 @default.
- W2135756073 hasConcept C178790620 @default.
- W2135756073 hasConcept C185592680 @default.
- W2135756073 hasConcept C188027245 @default.
- W2135756073 hasConcept C190062978 @default.
- W2135756073 hasConcept C192562407 @default.
- W2135756073 hasConcept C521977710 @default.
- W2135756073 hasConcept C55493867 @default.
- W2135756073 hasConcept C67407626 @default.
- W2135756073 hasConcept C79879829 @default.
- W2135756073 hasConcept C86803240 @default.
- W2135756073 hasConceptScore W2135756073C108586683 @default.
- W2135756073 hasConceptScore W2135756073C12554922 @default.
- W2135756073 hasConceptScore W2135756073C15920480 @default.
- W2135756073 hasConceptScore W2135756073C161478664 @default.
- W2135756073 hasConceptScore W2135756073C171250308 @default.