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- W2135918042 abstract "EDITORIAL COMMENT: We asked the authors to explain what a Schilling test was and they provided the following explanation. The Schilling test is used to determine whether there is failure of vitamin B12 absorption due to a lack of gastric intrinsic factor. The patient is given radioactive labelled vitamin B12 orally and unlabelled vitamin B12 by intramuscular injection. The portion of administered radioactivity excreted in the urine over a 24-hour period provides a measurement of B12 absorption. Patients with B12 deficiency secondary to pernicious anaemia will have low excretion of administered radioactivity. The test is then repeated adding intrinsic factor to the oral dose of labelled vitamin B12. In pernicious anaemia the absorption of the vitamin will now approach normal. Summary: We report a case of polyglandular autoimmune deficiency presenting during pregnancy which was associated with a favourable outcome for both mother and fetus (apart from fetal growth retardation) with appropriate replacement therapy and adequate steroid cover at the time of delivery." @default.
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- W2135918042 date "1998-11-01" @default.
- W2135918042 modified "2023-09-23" @default.
- W2135918042 title "Polyglandular Autoimmune Syndrome Type 2 Presenting for the First Time During Pregnancy" @default.
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- W2135918042 doi "https://doi.org/10.1111/j.1479-828x.1998.tb03110.x" @default.
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