Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135956246> ?p ?o ?g. }
- W2135956246 endingPage "55" @default.
- W2135956246 startingPage "51" @default.
- W2135956246 abstract "<b>Background:</b> Recent data have outlined a relationship between the composition of the intestinal microflora and allergic inflammation, and demonstrated the competence of probiotics in downregulation of such inflammation. <b>Aims:</b> Our aims were to characterise the relationship between gut microbes and the extent of allergic sensitisation and to assess whether the efficacy of bifidobacterial supplementation in the treatment of allergy could relate to modulation of the intestinal microbiota. <b>Methods:</b> This randomised study included 21 infants with early onset atopic eczema of whom eight were intolerant (highly sensitised group (HSG)) and 13 tolerant (sensitised group (SG)) to extensively hydrolysed whey formula (EHF). In the SG, six were weaned to EHF without (placebo group (PG)) and seven to EHF with <i>Bifidobacterium lactis</i> Bb-12 supplementation (bifidobacteria treated group (BbG)). The faecal microflora of infants in the HSG was analysed only before weaning whereas in the SG the faecal microflora was analysed both before and after weaning. <b>Results:</b> Infants in the HSG had greater numbers of lactobacilli/enterococci than those in the SG. Serum total IgE concentration correlated directly with <i>Escherichia coli</i> counts in all infants and with bacteroides counts in the HSG, indicating that the presence of these bacteria is associated with the extent of atopic sensitisation. The effect of supplementation was characterised as a decrease in the numbers of <i>Escherichia coli</i> and protection against an increase in bacteroides numbers during weaning. <b>Conclusions:</b> These data indicate that bifidobacterial supplementation appears to modify the gut microbiota in a manner that may alleviate allergic inflammation. Further studies are needed to confirm this conclusion." @default.
- W2135956246 created "2016-06-24" @default.
- W2135956246 creator A5050767971 @default.
- W2135956246 creator A5054286955 @default.
- W2135956246 creator A5070824369 @default.
- W2135956246 creator A5072093984 @default.
- W2135956246 date "2002-07-01" @default.
- W2135956246 modified "2023-10-05" @default.
- W2135956246 title "Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?" @default.
- W2135956246 cites W1511823445 @default.
- W2135956246 cites W1524217669 @default.
- W2135956246 cites W1527957830 @default.
- W2135956246 cites W1549149232 @default.
- W2135956246 cites W1573276067 @default.
- W2135956246 cites W1575273264 @default.
- W2135956246 cites W1836546986 @default.
- W2135956246 cites W1838472043 @default.
- W2135956246 cites W1928953700 @default.
- W2135956246 cites W1971541867 @default.
- W2135956246 cites W1977715446 @default.
- W2135956246 cites W1978162071 @default.
- W2135956246 cites W1983002183 @default.
- W2135956246 cites W1988066089 @default.
- W2135956246 cites W1992153121 @default.
- W2135956246 cites W1993338100 @default.
- W2135956246 cites W1994993924 @default.
- W2135956246 cites W2000452395 @default.
- W2135956246 cites W2005628478 @default.
- W2135956246 cites W2008800123 @default.
- W2135956246 cites W2009296652 @default.
- W2135956246 cites W2021013876 @default.
- W2135956246 cites W2025092369 @default.
- W2135956246 cites W2028064677 @default.
- W2135956246 cites W2031205409 @default.
- W2135956246 cites W2040083365 @default.
- W2135956246 cites W2045337037 @default.
- W2135956246 cites W2046931787 @default.
- W2135956246 cites W2050210989 @default.
- W2135956246 cites W2052038013 @default.
- W2135956246 cites W2053714425 @default.
- W2135956246 cites W2056531858 @default.
- W2135956246 cites W2058324295 @default.
- W2135956246 cites W2058347393 @default.
- W2135956246 cites W2059825445 @default.
- W2135956246 cites W2061574098 @default.
- W2135956246 cites W2072303124 @default.
- W2135956246 cites W2084449401 @default.
- W2135956246 cites W2086045209 @default.
- W2135956246 cites W2088215709 @default.
- W2135956246 cites W2090631845 @default.
- W2135956246 cites W2093003072 @default.
- W2135956246 cites W2116329881 @default.
- W2135956246 cites W2124347780 @default.
- W2135956246 cites W2129001596 @default.
- W2135956246 cites W2131114862 @default.
- W2135956246 cites W2131291912 @default.
- W2135956246 cites W2136848239 @default.
- W2135956246 cites W2138253380 @default.
- W2135956246 cites W2144785793 @default.
- W2135956246 cites W2154264360 @default.
- W2135956246 cites W2157172492 @default.
- W2135956246 cites W2167497377 @default.
- W2135956246 cites W2417343246 @default.
- W2135956246 cites W2593244680 @default.
- W2135956246 cites W4300874554 @default.
- W2135956246 cites W75155212 @default.
- W2135956246 doi "https://doi.org/10.1136/gut.51.1.51" @default.
- W2135956246 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1773282" @default.
- W2135956246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12077091" @default.
- W2135956246 hasPublicationYear "2002" @default.
- W2135956246 type Work @default.
- W2135956246 sameAs 2135956246 @default.
- W2135956246 citedByCount "293" @default.
- W2135956246 countsByYear W21359562462012 @default.
- W2135956246 countsByYear W21359562462013 @default.
- W2135956246 countsByYear W21359562462014 @default.
- W2135956246 countsByYear W21359562462015 @default.
- W2135956246 countsByYear W21359562462016 @default.
- W2135956246 countsByYear W21359562462017 @default.
- W2135956246 countsByYear W21359562462018 @default.
- W2135956246 countsByYear W21359562462019 @default.
- W2135956246 countsByYear W21359562462020 @default.
- W2135956246 countsByYear W21359562462021 @default.
- W2135956246 countsByYear W21359562462022 @default.
- W2135956246 countsByYear W21359562462023 @default.
- W2135956246 crossrefType "journal-article" @default.
- W2135956246 hasAuthorship W2135956246A5050767971 @default.
- W2135956246 hasAuthorship W2135956246A5054286955 @default.
- W2135956246 hasAuthorship W2135956246A5070824369 @default.
- W2135956246 hasAuthorship W2135956246A5072093984 @default.
- W2135956246 hasBestOaLocation W21359562461 @default.
- W2135956246 hasConcept C100544194 @default.
- W2135956246 hasConcept C104317684 @default.
- W2135956246 hasConcept C126322002 @default.
- W2135956246 hasConcept C143121216 @default.
- W2135956246 hasConcept C203014093 @default.
- W2135956246 hasConcept C207480886 @default.
- W2135956246 hasConcept C2777785397 @default.