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• W2135965057 abstract "Non-pharmacological interventions have important therapeutic potential for cognitive decline. Cognitive training and reminiscence therapy are used widely for this indication, but the evidence remains inconclusive. Technology has a growing relevance in the field of cognition. We thus designed a study using computer-based programs for cognitive training and reminiscence therapy in subjects with cognitive impairment and dementia. We performed a randomized controlled study to evaluate two computerized interventions, namely personalized reminiscence therapy and cognitive training. The reminiscence system was developed specifically for the purpose of this study and the cognitive training system utilized the Savion software program. Participants in adult day-care centers older than 65 years with cognitive impairment or dementia were randomized to either one of the interventions or to a control group, where subjects continued usual activities. Outcome measures included global cognitive function (using the Mindstreams computerized cognitive assessment battery), well-being (using QoL-AD, Will To Live and NPI questionnaires), and caregiver burden (using the short version of Zarit Caregiver Burden Interview). The study received institutional Ethics Committee approval. Of the 167 subjects recruited for the study, 95 were suitable for randomization to one of the study arms. Subjects in the intervention groups participated in 2 supervised weekly sessions of 30-minute duration each, for a period of 3 months. Assessments were performed at baseline, at one month (T1) and at 3 months (T3). When comparing the reminiscence group vs. the control group, group effects were found at both T1 and T3 for the following variables: global cognitive score, QoL-AD-patient and WTL. When comparing the cognitive training and the control groups, group effect was found only at T1 for orientation. Although this study found promising results for both the computer-based reminiscence and cognitive training interventions, the findings were not adequate to draw firm conclusions. More randomized controlled trials with a greater sample size and longer periods of evaluation should be encouraged." @default.
• W2135965057 created "2016-06-24" @default.
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• W2135965057 date "2014-07-01" @default.
• W2135965057 modified "2023-09-27" @default.
• W2135965057 title "F2-01-03: COMPUTER-SUPPORTED PERSONAL INTERVENTIONS FOR OLDER PEOPLE WITH COGNITIVE IMPAIRMENT AND DEMENTIA" @default.
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• W2135965057 doi "https://doi.org/10.1016/j.jalz.2014.04.137" @default.
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