Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135993485> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2135993485 abstract "The onset of dynamic exercise typically exhibits a triphasic blood pressure (BP) response, consisting of an initial rise (0-3s) followed by a transient drop below resting levels (4-10s) and then a sustained increase (>10s). We investigated the role of skeletal muscle afferents in modulating the dynamics of BP at the onset of exercise. Beat-to-beat BP (brachial artery), heart rate (HR), stroke volume (SV), cardiac output (CO) were continuously monitored in 8 healthy men (28±3 yr) while performing leg cycling exercise (80W) under control (CTRL) and lumbar intrathecal fentanyl (FENT) (impairing cephalad projection of opioid receptor sensitive muscle afferents). To evaluate whether cephalad migration of fentanyl affected cardiovascular control centers, we assessed the pressor response to handgrip exercise in both conditions. At the exercise onset, mean BP increased from baseline in the first 3s (+5±1 mmHg, P<0.05) and decreased to a nadir at 10s (-4±3 mmHg, P<0.05). Fentanyl did not affect BP response during the first 10s, but blunted its increase thereafter (CTRL: +9±3 vs. FENT: 0±2 mmHg at 50s; P<0.05). HR, SV and CO responses to exercise were not affected by fentanyl. Similar mean BP responses to static handgrip in both conditions indicated that cephalad migration of fentanyl was avoided. Our findings demonstrate an important contribution of group III/IV muscle afferent fibers to BP response to leg cycling exercise. Grant Funding Source: Supported by the Brazilian Science Without Borders Program" @default.
- W2135993485 created "2016-06-24" @default.
- W2135993485 creator A5003221419 @default.
- W2135993485 creator A5014150118 @default.
- W2135993485 creator A5017228450 @default.
- W2135993485 creator A5029573536 @default.
- W2135993485 creator A5050361725 @default.
- W2135993485 creator A5082967319 @default.
- W2135993485 creator A5085838808 @default.
- W2135993485 date "2014-04-01" @default.
- W2135993485 modified "2023-10-16" @default.
- W2135993485 title "Group III/IV muscle afferents are important for the pressor response to dynamic exercise in healthy humans (1165.9)" @default.
- W2135993485 doi "https://doi.org/10.1096/fasebj.28.1_supplement.1165.9" @default.
- W2135993485 hasPublicationYear "2014" @default.
- W2135993485 type Work @default.
- W2135993485 sameAs 2135993485 @default.
- W2135993485 citedByCount "0" @default.
- W2135993485 crossrefType "journal-article" @default.
- W2135993485 hasAuthorship W2135993485A5003221419 @default.
- W2135993485 hasAuthorship W2135993485A5014150118 @default.
- W2135993485 hasAuthorship W2135993485A5017228450 @default.
- W2135993485 hasAuthorship W2135993485A5029573536 @default.
- W2135993485 hasAuthorship W2135993485A5050361725 @default.
- W2135993485 hasAuthorship W2135993485A5082967319 @default.
- W2135993485 hasAuthorship W2135993485A5085838808 @default.
- W2135993485 hasConcept C126322002 @default.
- W2135993485 hasConcept C134018914 @default.
- W2135993485 hasConcept C164705383 @default.
- W2135993485 hasConcept C2777953023 @default.
- W2135993485 hasConcept C2779959927 @default.
- W2135993485 hasConcept C2781072394 @default.
- W2135993485 hasConcept C3019263340 @default.
- W2135993485 hasConcept C42219234 @default.
- W2135993485 hasConcept C71924100 @default.
- W2135993485 hasConcept C84393581 @default.
- W2135993485 hasConceptScore W2135993485C126322002 @default.
- W2135993485 hasConceptScore W2135993485C134018914 @default.
- W2135993485 hasConceptScore W2135993485C164705383 @default.
- W2135993485 hasConceptScore W2135993485C2777953023 @default.
- W2135993485 hasConceptScore W2135993485C2779959927 @default.
- W2135993485 hasConceptScore W2135993485C2781072394 @default.
- W2135993485 hasConceptScore W2135993485C3019263340 @default.
- W2135993485 hasConceptScore W2135993485C42219234 @default.
- W2135993485 hasConceptScore W2135993485C71924100 @default.
- W2135993485 hasConceptScore W2135993485C84393581 @default.
- W2135993485 hasIssue "S1" @default.
- W2135993485 hasLocation W21359934851 @default.
- W2135993485 hasOpenAccess W2135993485 @default.
- W2135993485 hasPrimaryLocation W21359934851 @default.
- W2135993485 hasRelatedWork W1966234050 @default.
- W2135993485 hasRelatedWork W1974568996 @default.
- W2135993485 hasRelatedWork W2016840789 @default.
- W2135993485 hasRelatedWork W2081376013 @default.
- W2135993485 hasRelatedWork W2144576666 @default.
- W2135993485 hasRelatedWork W2309978229 @default.
- W2135993485 hasRelatedWork W2383375557 @default.
- W2135993485 hasRelatedWork W2463478234 @default.
- W2135993485 hasRelatedWork W3028691777 @default.
- W2135993485 hasRelatedWork W3166675052 @default.
- W2135993485 hasVolume "28" @default.
- W2135993485 isParatext "false" @default.
- W2135993485 isRetracted "false" @default.
- W2135993485 magId "2135993485" @default.
- W2135993485 workType "article" @default.