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• W2136091715 abstract "Juvenile coho salmon undergo a complex transition of morphological, behavioural and physiological parameters which tranform the freshwater parr to a seawater-adaptable smolt. To investigate the suspected role(s) of growth hormone (GH)in smoltification, a series of experiments were performed. The first set of experiments examined effects of exogenous GH on metabolism during smoltification. In parr and pre-smolts, but not in smolts, GH treatment induced a 2-fold hyperglycemia. No effects were observed on plasma amino acid nitrogen or fatty acid levels. Additionally, there were no consistent effects noted in muscle protein or amino acid nitrogen levels. The results are discussed in terms of tissue sensitivities and teleost metabolic rates. The major study on smoltification and GH consisted of two seasons of weekly sampling experiments, encompassing smoltification and subsequent desmoltification. Increases in plasma GH levels during smoltification were noted in both studies. These increases were correlated with changes in plasma and tissue metabolite levels, as well as with changes in growth patterns. The significance of these changes and interrelationships are discussed with reference to the dynamic aspects of smoltification, including external influences. Fish undergoing desmoltification also displayed elevated GH Pevels, although metabolite levels appeared to be reverting to the freshwater state. Functions of GH in these animals are also discussed. The second phase of the thesis focused on actual seawater adaptation, examining the proposed hypoosmoregulatory actions of GH. Seawater transfer led to rapid and dramatic increases in plasma GH, followed by changes in carbohydrate and lipid metabolism. These changes occur as plasma ion regulation begins. Pretreatment with somatostatin, a biological inhibitor of GH" @default.
• W2136091715 created "2016-06-24" @default.
• W2136091715 creator A5050581861 @default.
• W2136091715 date "1989-01-01" @default.
• W2136091715 modified "2023-09-27" @default.
• W2136091715 title "ASPECTS OF GROWTH HORMONE IN THE PHYSIOLOGY OF SMOLTIFICATION AND SEAWATER ADAPTATION OF COHO SALMON" @default.
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