Matches in SemOpenAlex for { <https://semopenalex.org/work/W2136094762> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2136094762 abstract "Summary . Tetrahydrobiopterine (BH 4 ) and its relatives are classified as unconjugated pteridines or pterins distinguishing them from the folates. BH 4 is not a vitamin for mammals, since they can synthesize it. GTP is the major precursor of atoms in the pterin nucleus. The initial step in this pathway is conversion of GTP to D-erythro-7, 8-dihydroneopterin triphosphate, a reaction catalyzed by the enzyme GTP-cyclohydrolase I (EC 3.5.4.16; GTP-CH). There are many important metabolic functions of BH 4 : it is a crucial cofactor in hydroxylation reactions of phenylalanine, tyrosine and tryptophane. The finding of BH 4 participation in monoaminergic neurotransmitter metabolism regulation contributed to the knowledge of atipic neurological symptoms in some kinds of phenylketonuric children. As a cofactor of nitric oxide syntheses BH 4 is a crucial metabolite involved in physiological function of cardiovascular system. The literature data confirm that the BH 4 depletion is crucial in the control of both NO and superoxide generation (H" @default.
- W2136094762 created "2016-06-24" @default.
- W2136094762 creator A5020093251 @default.
- W2136094762 date "2004-01-01" @default.
- W2136094762 modified "2023-09-24" @default.
- W2136094762 title "BIOCHEMICAL FUNCTIONS AND CLINICAL IMPORTANCE OF UNCONJUGATED PTERIDINES" @default.
- W2136094762 cites W1581503432 @default.
- W2136094762 cites W1584615699 @default.
- W2136094762 cites W1585340447 @default.
- W2136094762 cites W1913227784 @default.
- W2136094762 cites W1973549601 @default.
- W2136094762 cites W1979414168 @default.
- W2136094762 cites W1995572986 @default.
- W2136094762 cites W1999646284 @default.
- W2136094762 cites W2004600216 @default.
- W2136094762 cites W2015562068 @default.
- W2136094762 cites W2026425756 @default.
- W2136094762 cites W2037000455 @default.
- W2136094762 cites W2058242086 @default.
- W2136094762 cites W2082566746 @default.
- W2136094762 cites W2087040026 @default.
- W2136094762 cites W2097851088 @default.
- W2136094762 cites W2107513604 @default.
- W2136094762 cites W2124874936 @default.
- W2136094762 cites W2128399345 @default.
- W2136094762 cites W2136857318 @default.
- W2136094762 cites W2166865140 @default.
- W2136094762 cites W992556388 @default.
- W2136094762 hasPublicationYear "2004" @default.
- W2136094762 type Work @default.
- W2136094762 sameAs 2136094762 @default.
- W2136094762 citedByCount "3" @default.
- W2136094762 countsByYear W21360947622012 @default.
- W2136094762 crossrefType "journal-article" @default.
- W2136094762 hasAuthorship W2136094762A5020093251 @default.
- W2136094762 hasConcept C118716 @default.
- W2136094762 hasConcept C181199279 @default.
- W2136094762 hasConcept C185592680 @default.
- W2136094762 hasConcept C197957613 @default.
- W2136094762 hasConcept C2776055822 @default.
- W2136094762 hasConcept C2776145790 @default.
- W2136094762 hasConcept C2776165026 @default.
- W2136094762 hasConcept C2777431362 @default.
- W2136094762 hasConcept C2777451243 @default.
- W2136094762 hasConcept C2777477808 @default.
- W2136094762 hasConcept C2781109383 @default.
- W2136094762 hasConcept C515207424 @default.
- W2136094762 hasConcept C55493867 @default.
- W2136094762 hasConcept C71240020 @default.
- W2136094762 hasConceptScore W2136094762C118716 @default.
- W2136094762 hasConceptScore W2136094762C181199279 @default.
- W2136094762 hasConceptScore W2136094762C185592680 @default.
- W2136094762 hasConceptScore W2136094762C197957613 @default.
- W2136094762 hasConceptScore W2136094762C2776055822 @default.
- W2136094762 hasConceptScore W2136094762C2776145790 @default.
- W2136094762 hasConceptScore W2136094762C2776165026 @default.
- W2136094762 hasConceptScore W2136094762C2777431362 @default.
- W2136094762 hasConceptScore W2136094762C2777451243 @default.
- W2136094762 hasConceptScore W2136094762C2777477808 @default.
- W2136094762 hasConceptScore W2136094762C2781109383 @default.
- W2136094762 hasConceptScore W2136094762C515207424 @default.
- W2136094762 hasConceptScore W2136094762C55493867 @default.
- W2136094762 hasConceptScore W2136094762C71240020 @default.
- W2136094762 hasLocation W21360947621 @default.
- W2136094762 hasOpenAccess W2136094762 @default.
- W2136094762 hasPrimaryLocation W21360947621 @default.
- W2136094762 hasRelatedWork W1033901898 @default.
- W2136094762 hasRelatedWork W1715374218 @default.
- W2136094762 hasRelatedWork W2014586066 @default.
- W2136094762 hasRelatedWork W2034533322 @default.
- W2136094762 hasRelatedWork W2035127982 @default.
- W2136094762 hasRelatedWork W2039935294 @default.
- W2136094762 hasRelatedWork W2073167703 @default.
- W2136094762 hasRelatedWork W2094370941 @default.
- W2136094762 hasRelatedWork W2162473589 @default.
- W2136094762 hasRelatedWork W2225461623 @default.
- W2136094762 hasRelatedWork W2748150188 @default.
- W2136094762 hasRelatedWork W995978037 @default.
- W2136094762 isParatext "false" @default.
- W2136094762 isRetracted "false" @default.
- W2136094762 magId "2136094762" @default.
- W2136094762 workType "article" @default.