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- W2136124744 abstract "The knowledge about the existence of different pathways for the repairing of DNA lesions has made possible a better understanding of mutation processes. The double mutant method has been shown to be useful for grouping rad mutants in yeast. Through this method, three different groups of repair mechanisms were found: (a) RAD3 group corresponding to the excision repair of UV lesions, (b) RAD6 group corresponding to the translesion type of post-replication repair and, (c) RAD52 group corresponding to the recombination type of post-replication repair. In this work, a search for a classification of Drosophila mus mutants in groups analogous to yeast RAD groups is done. Information obtained by double mutant studies was integrated with that obtained by biochemical, recombination, DNA damaging agent sensitivity and mutation studies. The following groups were found: (a) group of mei9 and mus201, analogous to RAD3, (b) group of mei41 and mus302 analogous to RAD52 and, (c) group of mus104 and mus101 analogous to RAD6. In addition, there are mutants that belong to a group corresponding to pre-replication repair of MMS lesions such as mus103, mus306 and mus207. As a peculiarity of Drosophila, it was found that interaction between pre- and post-replication repair mechanisms is indifferent and not synergistic as was found in yeast. A possible explanation could be a weaker control of post-replication repair mechanisms in Drosophila than in yeast. It is expected that this research could help for a better understanding of repair mechanisms in complex organisms." @default.
- W2136124744 created "2016-06-24" @default.
- W2136124744 creator A5025542893 @default.
- W2136124744 date "1998-02-01" @default.
- W2136124744 modified "2023-09-26" @default.
- W2136124744 title "Search for DNA repair pathways in Drosophila melanogaster" @default.
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- W2136124744 cites W1482271238 @default.
- W2136124744 cites W1485725156 @default.
- W2136124744 cites W1557050195 @default.
- W2136124744 cites W1755033191 @default.
- W2136124744 cites W1823692221 @default.
- W2136124744 cites W1882526720 @default.
- W2136124744 cites W1905205929 @default.
- W2136124744 cites W1908345703 @default.
- W2136124744 cites W1912204041 @default.
- W2136124744 cites W1923728284 @default.
- W2136124744 cites W1933256326 @default.
- W2136124744 cites W1964681550 @default.
- W2136124744 cites W1964695995 @default.
- W2136124744 cites W1967653471 @default.
- W2136124744 cites W1973997983 @default.
- W2136124744 cites W1981900473 @default.
- W2136124744 cites W1984353960 @default.
- W2136124744 cites W1984436184 @default.
- W2136124744 cites W1984523715 @default.
- W2136124744 cites W1988072121 @default.
- W2136124744 cites W1988175651 @default.
- W2136124744 cites W1995563044 @default.
- W2136124744 cites W2001586358 @default.
- W2136124744 cites W2003686338 @default.
- W2136124744 cites W2004674262 @default.
- W2136124744 cites W2007545121 @default.
- W2136124744 cites W2014319497 @default.
- W2136124744 cites W2015404276 @default.
- W2136124744 cites W2016981297 @default.
- W2136124744 cites W2017044906 @default.
- W2136124744 cites W2023399964 @default.
- W2136124744 cites W2030327904 @default.
- W2136124744 cites W2031867299 @default.
- W2136124744 cites W2032551621 @default.
- W2136124744 cites W2032650113 @default.
- W2136124744 cites W2037728854 @default.
- W2136124744 cites W2039622727 @default.
- W2136124744 cites W2045887257 @default.
- W2136124744 cites W2047733433 @default.
- W2136124744 cites W2052960896 @default.
- W2136124744 cites W2054043758 @default.
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- W2136124744 cites W2058420479 @default.
- W2136124744 cites W2058565567 @default.
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- W2136124744 cites W2062407642 @default.
- W2136124744 cites W2067461303 @default.
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- W2136124744 cites W2075634121 @default.
- W2136124744 cites W2081379588 @default.
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- W2136124744 cites W2085271212 @default.
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- W2136124744 cites W2097475918 @default.
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- W2136124744 cites W2101817433 @default.
- W2136124744 cites W2101856937 @default.
- W2136124744 cites W2103742481 @default.
- W2136124744 cites W2126830955 @default.
- W2136124744 cites W2128774980 @default.
- W2136124744 cites W2130394151 @default.
- W2136124744 cites W2136238750 @default.
- W2136124744 cites W2136850428 @default.
- W2136124744 cites W2138476183 @default.
- W2136124744 cites W2140360876 @default.
- W2136124744 cites W2155755872 @default.
- W2136124744 cites W2174240372 @default.
- W2136124744 cites W2174994538 @default.
- W2136124744 cites W2416194960 @default.
- W2136124744 cites W2614231071 @default.
- W2136124744 cites W3021924335 @default.
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- W2136124744 doi "https://doi.org/10.1016/s0921-8777(97)00063-3" @default.
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- W2136124744 hasPublicationYear "1998" @default.
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