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• W2136184028 abstract "Abstract The relative importance of different modes of gene expression of viability genes contributing to inbreeding depression was investigated in the wild plant, Mimulus guttatus. Viability genes were identified by self-fertilizing 31 outbred plants, each heterozygous for three to nine unlinked allozyme markers, and analyzing segregation ratios of selfed progeny at maturity for deviations from 1:2:1 ratios. In this study, 24 linkages of viability genes to marker loci were detected. To infer the nature of gene action for these viability genes, a model-free graphical method was developed that examines the space of segregation ratios allowed by each of seven selection models (i.e., overdominance, complete recessivity, partial recessivity, additivity, partial dominance, complete dominance and underdominance). Using this method, we found that, of 24 linkages detected, 18 were consistent with either partial dominance, complete dominance or underdominance. Six were consistent with either partial recessivity, complete recessivity or overdominance. This finding indicates that, in these chromosomal segments identified by allozyme markers, partial dominance plays the predominant role in inbreeding depression. This is inconsistent with either the dominance or overdominance hypotheses proposed to account for inbreeding depression." @default.
• W2136184028 created "2016-06-24" @default.
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• W2136184028 date "1994-01-01" @default.
• W2136184028 modified "2023-10-03" @default.
• W2136184028 title "Evidence for the partial dominance of viability genes contributing to inbreeding depression in Mimulus guttatus." @default.
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• W2136184028 doi "https://doi.org/10.1093/genetics/136.1.323" @default.
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