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- W2136217164 abstract "The phosphoinositide 3-kinases (PI3-kinases) are a family of lipid kinases that have a key role in the regulation of many cellular processes including proliferation, survival, carbohydrate metabolism, and motility. There is now strong evidence that some members of the PI3-kinase family have an important role in cancer. Emerging evidence for functional specialisation of PI3-kinase isoforms suggests that isoform selective inhibitors, in contrast to the existing non-selective inhibitors wortmannin and LY294002, may prove to be useful anticancer drugs." @default.
- W2136217164 created "2016-06-24" @default.
- W2136217164 creator A5014159829 @default.
- W2136217164 date "2001-09-01" @default.
- W2136217164 modified "2023-10-16" @default.
- W2136217164 title "Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment." @default.
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- W2136217164 doi "https://doi.org/10.1677/erc.0.0080237" @default.
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