FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2136333721> ?p ?o ?g. }

• W2136333721 endingPage "3330" @default.
• W2136333721 startingPage "3320" @default.
• W2136333721 abstract "ABSTRACT Lyme disease is a multisystemic disorder caused by Borrelia burgdorferi infection. Upon infection, some B. burgdorferi genes are upregulated, including members of the microbial surface components recognizing adhesive matrix molecule (MSCRAMM) protein family, which facilitate B. burgdorferi adherence to extracellular matrix components of the host. Comparative genome analysis has revealed a new family of B. burgdorferi proteins containing the von Willebrand factor A (vWFA) domain. In the present study, we characterized the expression and membrane association of the vWFA domain-containing protein BB0172 by using in vitro transcription/translation systems in the presence of microsomal membranes and with detergent phase separation assays. Our results showed evidence of BB0172 localization in the outer membrane, the orientation of the vWFA domain to the extracellular environment, and its function as a metal ion-dependent integrin-binding protein. This is the first report of a borrelial adhesin with a metal ion-dependent adhesion site (MIDAS) motif that is similar to those observed in eukaryotic integrins and has a similar function." @default.
• W2136333721 created "2016-06-24" @default.
• W2136333721 creator A5021137999 @default.
• W2136333721 creator A5026194186 @default.
• W2136333721 creator A5055695025 @default.
• W2136333721 creator A5082168636 @default.
• W2136333721 date "2013-08-01" @default.
• W2136333721 modified "2023-10-15" @default.
• W2136333721 title "BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin α ₃ β ₁" @default.
• W2136333721 cites W1572374978 @default.
• W2136333721 cites W1859579625 @default.
• W2136333721 cites W1942941883 @default.
• W2136333721 cites W1964571929 @default.
• W2136333721 cites W1966103266 @default.
• W2136333721 cites W1970483666 @default.
• W2136333721 cites W1972470306 @default.
• W2136333721 cites W1977602054 @default.
• W2136333721 cites W1977613157 @default.
• W2136333721 cites W1982398946 @default.
• W2136333721 cites W1983580481 @default.
• W2136333721 cites W1989754927 @default.
• W2136333721 cites W1994320907 @default.
• W2136333721 cites W1996478334 @default.
• W2136333721 cites W1997698750 @default.
• W2136333721 cites W1999793224 @default.
• W2136333721 cites W2010088550 @default.
• W2136333721 cites W2012299366 @default.
• W2136333721 cites W2012615687 @default.
• W2136333721 cites W2012738583 @default.
• W2136333721 cites W2013636685 @default.
• W2136333721 cites W2015715780 @default.
• W2136333721 cites W2016555093 @default.
• W2136333721 cites W2018774638 @default.
• W2136333721 cites W2022262813 @default.
• W2136333721 cites W2025859600 @default.
• W2136333721 cites W2030246164 @default.
• W2136333721 cites W2054115369 @default.
• W2136333721 cites W2065940152 @default.
• W2136333721 cites W2068259161 @default.
• W2136333721 cites W2071119634 @default.
• W2136333721 cites W2071985786 @default.
• W2136333721 cites W2075089767 @default.
• W2136333721 cites W2079133863 @default.
• W2136333721 cites W2092695069 @default.
• W2136333721 cites W2093916196 @default.
• W2136333721 cites W2094201044 @default.
• W2136333721 cites W2098643925 @default.
• W2136333721 cites W2099584367 @default.
• W2136333721 cites W2107066422 @default.
• W2136333721 cites W2110425545 @default.
• W2136333721 cites W2111485154 @default.
• W2136333721 cites W2116073343 @default.
• W2136333721 cites W2116177758 @default.
• W2136333721 cites W2117919289 @default.
• W2136333721 cites W2118783042 @default.
• W2136333721 cites W2118870981 @default.
• W2136333721 cites W2126400679 @default.
• W2136333721 cites W2131717149 @default.
• W2136333721 cites W2134820637 @default.
• W2136333721 cites W2135597362 @default.
• W2136333721 cites W2135890775 @default.
• W2136333721 cites W2136252131 @default.
• W2136333721 cites W2138164643 @default.
• W2136333721 cites W2139474686 @default.
• W2136333721 cites W2140604657 @default.
• W2136333721 cites W2140974770 @default.
• W2136333721 cites W2141941210 @default.
• W2136333721 cites W2143361892 @default.
• W2136333721 cites W2146917428 @default.
• W2136333721 cites W2147671100 @default.
• W2136333721 cites W2149746012 @default.
• W2136333721 cites W2151156268 @default.
• W2136333721 cites W2152770371 @default.
• W2136333721 cites W2155639617 @default.
• W2136333721 cites W2159874398 @default.
• W2136333721 cites W2161237846 @default.
• W2136333721 cites W2164808173 @default.
• W2136333721 cites W2166799325 @default.
• W2136333721 cites W2169788329 @default.
• W2136333721 cites W2183743463 @default.
• W2136333721 cites W2313344452 @default.
• W2136333721 cites W40068663 @default.
• W2136333721 cites W4232671899 @default.
• W2136333721 cites W4242471323 @default.
• W2136333721 cites W4251025034 @default.
• W2136333721 cites W4321509040 @default.
• W2136333721 doi "https://doi.org/10.1128/jb.00187-13" @default.
• W2136333721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3719542" @default.
• W2136333721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23687274" @default.
• W2136333721 hasPublicationYear "2013" @default.
• W2136333721 type Work @default.
• W2136333721 sameAs 2136333721 @default.
• W2136333721 citedByCount "20" @default.
• W2136333721 countsByYear W21363337212014 @default.
• W2136333721 countsByYear W21363337212015 @default.
• W2136333721 countsByYear W21363337212016 @default.
• W2136333721 countsByYear W21363337212017 @default.
• W2136333721 countsByYear W21363337212018 @default.

• next