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- W2136489250 abstract "Buruli ulcer (Mycobacterium ulcerans infection) is a neglected tropical disease of skin and subcutaneous tissue that can result in long-term cosmetic and functional disability. It is a geographically restricted infection but transmission has been reported in endemic areas in more than 30 countries worldwide. The heaviest burden of disease lies in West and Sub-Saharan Africa where it affects children and adults in subsistence agricultural communities. Mycobacterium ulcerans infection is probably acquired via inoculation of the skin either directly from the environment or indirectly via insect bites. The environmental reservoir and exact route of transmission are not completely understood. It may be that the mode of acquisition varies in different parts of the world. Because of this uncertainty it has been nicknamed the 'mysterious disease'. The therapeutic approach has evolved in the past decade from aggressive surgical resection alone, to a greater focus on antibiotic therapy combined with adjunctive surgery." @default.
- W2136489250 created "2016-06-24" @default.
- W2136489250 creator A5025450411 @default.
- W2136489250 creator A5071271485 @default.
- W2136489250 date "2014-06-11" @default.
- W2136489250 modified "2023-10-14" @default.
- W2136489250 title "Epidemiology and management of Buruli ulcer" @default.
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- W2136489250 doi "https://doi.org/10.1586/14787210.2014.910113" @default.
- W2136489250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24918117" @default.
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