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• W2136548127 abstract "Abstract Background Dissociative drugs are used for chemical restraint in monkeys. The aim was to evaluate muscle relaxation, recovery, and ophthalmic and hemodynamic parameters in 24 capuchin monkeys subjected to four dissociative anesthesia protocols. Methods Animals were anesthetized with tiletamine–zolazepam ( TZ ), ketamine–xylazine ( KX ), ketamine–midazolam ( KM ), or ketamine–dexmedetomidine ( KD ). Muscle relaxation, digital reflex, lacrimal production, intraocular pressure ( IOP ), heart and respiratory rates, oxygen saturation ( S p O 2 ), rectal temperature, non‐invasive arterial blood pressure, palpebral and pupillary reflexes, and eyeball positioning were evaluated every 5 minutes for 20 minutes. Results Muscle relaxation was highest in KM and KD . At 5‐minute post‐injection, IOP was higher in TZ than in all other groups. There was a significant difference between groups and times in heart and respiratory rates and temperature. There were no significant differences in S p O 2, arterial blood pressure, and lacrimal production between groups. Conclusions The established parameters may help in clinical and ophthalmic examinations of primates." @default.
• W2136548127 created "2016-06-24" @default.
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• W2136548127 date "2015-10-12" @default.
• W2136548127 modified "2023-10-10" @default.
• W2136548127 title "Evaluation of ophthalmic and hemodynamic parameters in capuchin monkeys (<i>Sapajus</i> sp.) submitted to dissociative anesthetic protocols" @default.
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• W2136548127 doi "https://doi.org/10.1111/jmp.12200" @default.
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