Matches in SemOpenAlex for { <https://semopenalex.org/work/W2136611599> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2136611599 endingPage "554" @default.
- W2136611599 startingPage "551" @default.
- W2136611599 abstract "The phenomenon of cardiac memory refers to persistent response of the heart to an external pacing stimulus, where the response typically outlasts the stimulus. It is a fundamental tenet of neuroscience that synaptic modification is the basis of various forms of learning and memory. Drawing analogy with neural synapses and Gap Junctions (GJs) in the cardiac tissue, we had earlier hypothesized that dynamic, voltage-sensitive changes in GJ conductance may be related to the phenomenon of cardiac memory. In this paper we study a pair of Noble cardiac cell models, -originally proposed as a model of Purkinje cells, and capable of self-excited oscillations - coupled by dynamic GJs. The GJ conductance is allowed to vary as a function of junctional voltage. Simulations show the cell pair and GJ system has two stable states: one at a high value of GJ conductance and another at a lower value. The system can be switched between the two states by an appropriate external input. Such bistable dynamics can support memory operations and most probably underlie the phenomenon of cardiac memory." @default.
- W2136611599 created "2016-06-24" @default.
- W2136611599 creator A5000521454 @default.
- W2136611599 creator A5036309799 @default.
- W2136611599 creator A5080409383 @default.
- W2136611599 date "2006-01-01" @default.
- W2136611599 modified "2023-09-24" @default.
- W2136611599 title "Bistable behavior in a pair of interacting autorhythmic cardiac cell models: implications to cardiac memory" @default.
- W2136611599 cites W1896121363 @default.
- W2136611599 cites W1993766998 @default.
- W2136611599 cites W2010172543 @default.
- W2136611599 cites W2018737754 @default.
- W2136611599 cites W2078033190 @default.
- W2136611599 cites W2084464832 @default.
- W2136611599 cites W2085949935 @default.
- W2136611599 cites W2134982681 @default.
- W2136611599 cites W2159343782 @default.
- W2136611599 hasPublicationYear "2006" @default.
- W2136611599 type Work @default.
- W2136611599 sameAs 2136611599 @default.
- W2136611599 citedByCount "0" @default.
- W2136611599 crossrefType "proceedings-article" @default.
- W2136611599 hasAuthorship W2136611599A5000521454 @default.
- W2136611599 hasAuthorship W2136611599A5036309799 @default.
- W2136611599 hasAuthorship W2136611599A5080409383 @default.
- W2136611599 hasConcept C121332964 @default.
- W2136611599 hasConcept C15744967 @default.
- W2136611599 hasConcept C158157758 @default.
- W2136611599 hasConcept C169760540 @default.
- W2136611599 hasConcept C180747234 @default.
- W2136611599 hasConcept C185592680 @default.
- W2136611599 hasConcept C195221683 @default.
- W2136611599 hasConcept C2779918689 @default.
- W2136611599 hasConcept C49040817 @default.
- W2136611599 hasConcept C55493867 @default.
- W2136611599 hasConcept C79879829 @default.
- W2136611599 hasConcept C97292510 @default.
- W2136611599 hasConceptScore W2136611599C121332964 @default.
- W2136611599 hasConceptScore W2136611599C15744967 @default.
- W2136611599 hasConceptScore W2136611599C158157758 @default.
- W2136611599 hasConceptScore W2136611599C169760540 @default.
- W2136611599 hasConceptScore W2136611599C180747234 @default.
- W2136611599 hasConceptScore W2136611599C185592680 @default.
- W2136611599 hasConceptScore W2136611599C195221683 @default.
- W2136611599 hasConceptScore W2136611599C2779918689 @default.
- W2136611599 hasConceptScore W2136611599C49040817 @default.
- W2136611599 hasConceptScore W2136611599C55493867 @default.
- W2136611599 hasConceptScore W2136611599C79879829 @default.
- W2136611599 hasConceptScore W2136611599C97292510 @default.
- W2136611599 hasLocation W21366115991 @default.
- W2136611599 hasOpenAccess W2136611599 @default.
- W2136611599 hasPrimaryLocation W21366115991 @default.
- W2136611599 hasRelatedWork W1575832176 @default.
- W2136611599 hasRelatedWork W1596099105 @default.
- W2136611599 hasRelatedWork W1852972763 @default.
- W2136611599 hasRelatedWork W1972938482 @default.
- W2136611599 hasRelatedWork W1972940662 @default.
- W2136611599 hasRelatedWork W2002921152 @default.
- W2136611599 hasRelatedWork W2042310810 @default.
- W2136611599 hasRelatedWork W2046593988 @default.
- W2136611599 hasRelatedWork W2074584409 @default.
- W2136611599 hasRelatedWork W2075124934 @default.
- W2136611599 hasRelatedWork W2099186633 @default.
- W2136611599 hasRelatedWork W2109426757 @default.
- W2136611599 hasRelatedWork W2128110415 @default.
- W2136611599 hasRelatedWork W2142083285 @default.
- W2136611599 hasRelatedWork W2261262726 @default.
- W2136611599 hasRelatedWork W2273933424 @default.
- W2136611599 hasRelatedWork W2299599199 @default.
- W2136611599 hasRelatedWork W2460039088 @default.
- W2136611599 hasRelatedWork W2963424728 @default.
- W2136611599 hasRelatedWork W2107906060 @default.
- W2136611599 isParatext "false" @default.
- W2136611599 isRetracted "false" @default.
- W2136611599 magId "2136611599" @default.
- W2136611599 workType "article" @default.