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- W2136624276 abstract "The flavonoids as inhibitors of CYP1A1 exhibit chemopreventive effects against certain procarcinogens and have been considered as the promising cancer preventive agents. A series of novel 7,8-dimethoxy-α-naphthoflavones as the substrate analogs were designed and prepared. The enzyme assay suggested that all of these new flavones were stronger inhibitors of CYP1A1 than the lead compound α-naphthoflavone. Among the tested ones, 3h showed the most potent inhibitory effects." @default.
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- W2136624276 date "2013-03-01" @default.
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- W2136624276 title "Design and synthesis of new 7,8-dimethoxy-α-naphthoflavones as CYP1A1 inhibitors" @default.
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- W2136624276 doi "https://doi.org/10.1016/j.cclet.2013.01.006" @default.
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