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- W2136650023 abstract "Gingival overgrowth (GO) is a side effect associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressant, and calcium channel blockers. GO is characterized by the accumulation of extracellular matrix in gingival connective tissues, particularly collagenous components, with varying degrees of inflammation. One of the main drugs associated with GO is the antiepileptic phenytoin, which affects gingival tissues by altering extracellular matrix metabolism. Nevertheless, the pathogenesis of such drug-induced GO remains fulfilled by some contradictory findings. This paper aims to present the most relevant studies regarding the molecular, immune, and inflammatory aspects of phenytoin-induced gingival overgrowth." @default.
- W2136650023 created "2016-06-24" @default.
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- W2136650023 date "2011-07-25" @default.
- W2136650023 modified "2023-10-03" @default.
- W2136650023 title "Phenytoin-Induced Gingival Overgrowth: A Review of the Molecular, Immune, and Inflammatory Features" @default.
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- W2136650023 doi "https://doi.org/10.5402/2011/497850" @default.
- W2136650023 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3168966" @default.
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