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• W2136706649 abstract "Demethoxycarbonyl derivatives of aclacinomycin A and of its 7-epimer, 10-epi-aclacinomycinA and 4-O-methylaclacinomycin A were chemically derived from aclacinomycin A.The cytotoxicity and inhibitory effects on RNA and DNA synthesis in cultured L1210 leukemiacells of the 4-O-methyl derivative approximated that of aclacinomycin A, while the demethoxycarbonylderivatives and 10-epi-aclacinomycin A exhibited decreased activities in comparisonwith the parent compound." @default.
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• W2136706649 date "1980-01-01" @default.
• W2136706649 modified "2023-10-16" @default.
• W2136706649 title "Chemical modification of anthracycline antibiotics. I. Demethoxycarbonylation, 10-epimerization and 4-o-methylation of aclacinomycin A." @default.
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• W2136706649 doi "https://doi.org/10.7164/antibiotics.33.1323" @default.
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