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- W2136787401 abstract "Abstract 4-Hydroxyphenylacetic acid amides and 4-hydroxycinnamamides were synthesized and their antioxidant and neuroprotective activities were evaluated. Among the prepared compounds, 6f , 6g , 8b, and 9 exhibited potent inhibition of lipid peroxidation in rat brain homogenates, and marked DPPH radical scavenging activities. Furthermore, 6f , 6g , and 9 exhibited neuroprotective action against the oxidative damage induced by the exposure of primary cultured rat cortical cells to H2O2, xanthine/xanthine oxidase, or Fe2+/ascorbic acid. Based on these results, we found that 6f was the most potent antioxidant among the compounds tested." @default.
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- W2136787401 date "2002-09-01" @default.
- W2136787401 modified "2023-10-14" @default.
- W2136787401 title "Synthesis and Evaluation of 4-Hydroxyphenylacetic Acid Amides and 4-Hydroxycinnamamides as Antioxidants" @default.
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- W2136787401 doi "https://doi.org/10.1016/s0960-894x(02)00479-1" @default.
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