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- W2136826286 abstract "By the addition of 150 mM acetate into a batch culture at an initial pH of 6.8, the production of 2,3-butanediol (BDL) by Paenibacillus polymyxa reached 248 mM, yielding 0.87 mol·mol−1 glucose, where the ratio of acetate consumed to glucose consumed (A/C ratio) was calculated as 0.35 mol acetate mol−1 glucose. Therefore, a fed-batch culture was carried out by feeding glucose and acetate at a ratio of 0.35 mol acetate mol−1 glucose. In the fed-batch culture performed at pH 6.8, BDL production reached 637 mM, yielding 0.81 mol·mol−1 glucose, although the A/C ratio was only 0.18 mol acetate mol−1 glucose. By decreasing pH to 6.3 in the fed-batch culture, BDL production reached 566 mM, yielding 0.88 mol·mol−1 glucose and the A/C ratio was 0.32 mol acetate mol−1 glucose. The optical purity of BDL, which was expressed as enantiomeric excess, was retained at more than 98% of the (R, R)-stereoisomer at the end of culture, which was comparable to that without acetate addition." @default.
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- W2136826286 date "2000-01-01" @default.
- W2136826286 modified "2023-10-14" @default.
- W2136826286 title "Enhanced 2,3-butanediol production by addition of acetic acid in Paenibacillus polymyxa" @default.
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- W2136826286 doi "https://doi.org/10.1016/s1389-1723(00)90013-6" @default.
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