Matches in SemOpenAlex for { <https://semopenalex.org/work/W2136873422> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2136873422 abstract "Scleroderma is an autoimmune disease that involves the connective tissue characterized by skin fibrosis, classified as localized and systemic (participation of one or more internal organs). The primary objective of this study is to describe and analyze the clinical and laboratory findings in a group of children diagnosed with scleroderma at a referral hospital.Extraction of data from clinical charts of children with scleroderma in the rheumatology department at the Hospital Infantil de México Federico Gómez, between January 2000 and December 2007.Sixty two patients were included in the group. All of them completed the classification criteria for juvenile sclerodema, both systemic and localized. The mean age at diagnosis was 7.8 (1-14) years. The mean time from disease onset to diagnosis, based on clinical manifestations, was 23 months. The lesions found were: linear scleroderma (42%), mixed morphea (22%), circumscribed morphea (19%), generalized morphea (13%) and panclerotic morphea (4%). Involvement associated with Systemic Scleroderma was gastrointestinal 100% (18 patients), pulmonary 100% (18/18), Raynaud's phenomenon 89% (16/18), proximal sclerosis 89% (16/18), sclerodactilia 67% (12/18), joint pain 28% (5/18), calcinosis 56% (10/18). Positive antinuclear antibodies (ANA) were present in 14/62 (23%) patients (10 with systemic range and 4 localized), antiSCL 70 in 2/62 (4%) cases. The most common drug used was methotrexate.The most common skin lesions found were linear morphea, followed by the mixed and circumscribed types. In systemic scleroderma the most involved systems are the gastrointestinal, respiratory and vascular (associated with Raynaud's phenomenon). There is a special need for knowledge of this disease in first contact physicians for a faster and better diagnosis and treatment, in order to avoid complications. It is also necessary to improve resources in developing countries for complimentary studies, classification, treatment and follow-up." @default.
- W2136873422 created "2016-06-24" @default.
- W2136873422 creator A5004653857 @default.
- W2136873422 creator A5034226700 @default.
- W2136873422 creator A5050321223 @default.
- W2136873422 creator A5050409903 @default.
- W2136873422 date "2009-01-01" @default.
- W2136873422 modified "2023-09-29" @default.
- W2136873422 title "Clinical characteristics of children with scleroderma in a referral hospital" @default.
- W2136873422 cites W1969884422 @default.
- W2136873422 cites W2022783472 @default.
- W2136873422 cites W2060296628 @default.
- W2136873422 cites W2061062047 @default.
- W2136873422 cites W2081163651 @default.
- W2136873422 cites W2093885269 @default.
- W2136873422 cites W2138517681 @default.
- W2136873422 cites W2149389714 @default.
- W2136873422 cites W2162668424 @default.
- W2136873422 cites W2299513640 @default.
- W2136873422 doi "https://doi.org/10.1016/s2173-5743(09)70112-1" @default.
- W2136873422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21794601" @default.
- W2136873422 hasPublicationYear "2009" @default.
- W2136873422 type Work @default.
- W2136873422 sameAs 2136873422 @default.
- W2136873422 citedByCount "0" @default.
- W2136873422 crossrefType "journal-article" @default.
- W2136873422 hasAuthorship W2136873422A5004653857 @default.
- W2136873422 hasAuthorship W2136873422A5034226700 @default.
- W2136873422 hasAuthorship W2136873422A5050321223 @default.
- W2136873422 hasAuthorship W2136873422A5050409903 @default.
- W2136873422 hasConcept C126322002 @default.
- W2136873422 hasConcept C142724271 @default.
- W2136873422 hasConcept C149443304 @default.
- W2136873422 hasConcept C159654299 @default.
- W2136873422 hasConcept C16005928 @default.
- W2136873422 hasConcept C163764329 @default.
- W2136873422 hasConcept C180032290 @default.
- W2136873422 hasConcept C198451711 @default.
- W2136873422 hasConcept C203014093 @default.
- W2136873422 hasConcept C2775934546 @default.
- W2136873422 hasConcept C2775938904 @default.
- W2136873422 hasConcept C2776153627 @default.
- W2136873422 hasConcept C2776670291 @default.
- W2136873422 hasConcept C2777543607 @default.
- W2136873422 hasConcept C2777714996 @default.
- W2136873422 hasConcept C2778674544 @default.
- W2136873422 hasConcept C2778751314 @default.
- W2136873422 hasConcept C2779075594 @default.
- W2136873422 hasConcept C2779134260 @default.
- W2136873422 hasConcept C2779625490 @default.
- W2136873422 hasConcept C2779967694 @default.
- W2136873422 hasConcept C2780559512 @default.
- W2136873422 hasConcept C2910390209 @default.
- W2136873422 hasConcept C71924100 @default.
- W2136873422 hasConceptScore W2136873422C126322002 @default.
- W2136873422 hasConceptScore W2136873422C142724271 @default.
- W2136873422 hasConceptScore W2136873422C149443304 @default.
- W2136873422 hasConceptScore W2136873422C159654299 @default.
- W2136873422 hasConceptScore W2136873422C16005928 @default.
- W2136873422 hasConceptScore W2136873422C163764329 @default.
- W2136873422 hasConceptScore W2136873422C180032290 @default.
- W2136873422 hasConceptScore W2136873422C198451711 @default.
- W2136873422 hasConceptScore W2136873422C203014093 @default.
- W2136873422 hasConceptScore W2136873422C2775934546 @default.
- W2136873422 hasConceptScore W2136873422C2775938904 @default.
- W2136873422 hasConceptScore W2136873422C2776153627 @default.
- W2136873422 hasConceptScore W2136873422C2776670291 @default.
- W2136873422 hasConceptScore W2136873422C2777543607 @default.
- W2136873422 hasConceptScore W2136873422C2777714996 @default.
- W2136873422 hasConceptScore W2136873422C2778674544 @default.
- W2136873422 hasConceptScore W2136873422C2778751314 @default.
- W2136873422 hasConceptScore W2136873422C2779075594 @default.
- W2136873422 hasConceptScore W2136873422C2779134260 @default.
- W2136873422 hasConceptScore W2136873422C2779625490 @default.
- W2136873422 hasConceptScore W2136873422C2779967694 @default.
- W2136873422 hasConceptScore W2136873422C2780559512 @default.
- W2136873422 hasConceptScore W2136873422C2910390209 @default.
- W2136873422 hasConceptScore W2136873422C71924100 @default.
- W2136873422 hasLocation W21368734221 @default.
- W2136873422 hasLocation W21368734222 @default.
- W2136873422 hasOpenAccess W2136873422 @default.
- W2136873422 hasPrimaryLocation W21368734221 @default.
- W2136873422 isParatext "false" @default.
- W2136873422 isRetracted "false" @default.
- W2136873422 magId "2136873422" @default.
- W2136873422 workType "article" @default.