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• W2136883381 abstract "Activation of a cytotoxic T cell requires specific binding of antigenic peptides to major histocompatibility complex (MHC) molecules. This paper reports a study of peptides binding to members of the HLA-A3 superfamily using a recently developed 2D-QSAR method, called the additive method. Four alleles with high phenotype frequency were included in the study: A*0301, A*1101, A*3101 and A*6801. The influence of each of the 20 amino acids at each position of the peptide on binding was studied. A refined A3 supertype motif was defined in the study." @default.
• W2136883381 created "2016-06-24" @default.
• W2136883381 creator A5052238096 @default.
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• W2136883381 date "2003-01-01" @default.
• W2136883381 modified "2023-10-18" @default.
• W2136883381 title "HLA-A3 supermotif defined by quantitative structure–activity relationship analysis" @default.
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• W2136883381 doi "https://doi.org/10.1093/proeng/gzg005" @default.
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