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- W2136965692 abstract "During the routine screening of 152 patients with urticaria or angio-œdema for hypocomplementæmia, 4 patients were found to have low serum levels of the third component of complement (C). These patients were noteworthy and differed from previous reports of patients with urticaria-like skin lesions and hypocomplementæmia because of the absence of immune-complex disease. In addition to the low C3, 2 of these patients were unique on the basis of low serum levels of hæmolytic Cl, Clq, Cls, and properdin factor B, but normal concentrations of C4 and C2. These C abnormalities may reflect a new clinical entity, and these cases form the first description in man of the C1–bypass complement-activation pathway." @default.
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- W2136965692 date "2000-08-01" @default.
- W2136965692 modified "2023-10-16" @default.
- W2136965692 title "Modulation of the alternative complement pathway by C1 inhibitor (C1 INH)" @default.
- W2136965692 doi "https://doi.org/10.1016/s0162-3109(00)80168-x" @default.
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