Matches in SemOpenAlex for { <https://semopenalex.org/work/W2136993618> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2136993618 endingPage "2279" @default.
- W2136993618 startingPage "2272" @default.
- W2136993618 abstract "Three doses of sodium propionate (.75, 1.5, and 3.0 mmol/kg) were administered intravenously to 6, 8, and 14 dairy cows. Using first order kinetic analysis, the apparent plasma half-life increased significantly with increasing propionate dose. The apparent increase of propionate half-life with increasing propionate dose was attributed to saturation of uptake and disposal mechanisms. Using the nonlinear mathematical model of Henri-Michaelis-Menten for propionate concentrations at 3.0 mmol/kg, propionate half-life was significantly shorter than that obtained with the first order kinetic model. The Michaelis constant was 4.0 mM, the maximal rate of concentration decrease was .55 mM/min, half-life was 4.8 min, and distribution volume was .37 L/kg. Plasma glucose concentrations increased following all doses of propionate. The maximal increase in glucose concentration occurred earliest for the lowest dose and latest for the highest dose and increased in magnitude with increasing propionate dose. The plasma glucose response to intravenous propionate has been suggested as a measure of liver function in ruminants. Of the three propionate doses tested, the 3.0 mmol/kg dose appeared to saturate the uptake and disposal mechanisms of healthy liver and should be the most satisfactory dose for observing the plasma glucose response to injected propionate." @default.
- W2136993618 created "2016-06-24" @default.
- W2136993618 creator A5015911043 @default.
- W2136993618 creator A5063006965 @default.
- W2136993618 creator A5076953122 @default.
- W2136993618 date "1987-11-01" @default.
- W2136993618 modified "2023-10-17" @default.
- W2136993618 title "Nonlinear Pharmacokinetics and Conversion to Glucose of Intravenous Sodium Propionate in Dairy Cattle" @default.
- W2136993618 cites W2012267512 @default.
- W2136993618 cites W2019814726 @default.
- W2136993618 cites W2039319652 @default.
- W2136993618 cites W2045526589 @default.
- W2136993618 cites W2045916645 @default.
- W2136993618 cites W2061168344 @default.
- W2136993618 cites W2071401777 @default.
- W2136993618 cites W2149118959 @default.
- W2136993618 cites W2158690432 @default.
- W2136993618 cites W2160668327 @default.
- W2136993618 cites W2300936702 @default.
- W2136993618 cites W2331230203 @default.
- W2136993618 cites W2398639244 @default.
- W2136993618 cites W2989288127 @default.
- W2136993618 doi "https://doi.org/10.3168/jds.s0022-0302(87)80287-4" @default.
- W2136993618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3693632" @default.
- W2136993618 hasPublicationYear "1987" @default.
- W2136993618 type Work @default.
- W2136993618 sameAs 2136993618 @default.
- W2136993618 citedByCount "4" @default.
- W2136993618 countsByYear W21369936182012 @default.
- W2136993618 countsByYear W21369936182018 @default.
- W2136993618 crossrefType "journal-article" @default.
- W2136993618 hasAuthorship W2136993618A5015911043 @default.
- W2136993618 hasAuthorship W2136993618A5063006965 @default.
- W2136993618 hasAuthorship W2136993618A5076953122 @default.
- W2136993618 hasBestOaLocation W21369936181 @default.
- W2136993618 hasConcept C112705442 @default.
- W2136993618 hasConcept C126322002 @default.
- W2136993618 hasConcept C134018914 @default.
- W2136993618 hasConcept C139254425 @default.
- W2136993618 hasConcept C140793950 @default.
- W2136993618 hasConcept C178790620 @default.
- W2136993618 hasConcept C185592680 @default.
- W2136993618 hasConcept C2780014933 @default.
- W2136993618 hasConcept C2781271576 @default.
- W2136993618 hasConcept C537181965 @default.
- W2136993618 hasConcept C55493867 @default.
- W2136993618 hasConcept C71924100 @default.
- W2136993618 hasConcept C86803240 @default.
- W2136993618 hasConceptScore W2136993618C112705442 @default.
- W2136993618 hasConceptScore W2136993618C126322002 @default.
- W2136993618 hasConceptScore W2136993618C134018914 @default.
- W2136993618 hasConceptScore W2136993618C139254425 @default.
- W2136993618 hasConceptScore W2136993618C140793950 @default.
- W2136993618 hasConceptScore W2136993618C178790620 @default.
- W2136993618 hasConceptScore W2136993618C185592680 @default.
- W2136993618 hasConceptScore W2136993618C2780014933 @default.
- W2136993618 hasConceptScore W2136993618C2781271576 @default.
- W2136993618 hasConceptScore W2136993618C537181965 @default.
- W2136993618 hasConceptScore W2136993618C55493867 @default.
- W2136993618 hasConceptScore W2136993618C71924100 @default.
- W2136993618 hasConceptScore W2136993618C86803240 @default.
- W2136993618 hasIssue "11" @default.
- W2136993618 hasLocation W21369936181 @default.
- W2136993618 hasLocation W21369936182 @default.
- W2136993618 hasOpenAccess W2136993618 @default.
- W2136993618 hasPrimaryLocation W21369936181 @default.
- W2136993618 hasRelatedWork W1978954584 @default.
- W2136993618 hasRelatedWork W1985608818 @default.
- W2136993618 hasRelatedWork W2006202112 @default.
- W2136993618 hasRelatedWork W2032434058 @default.
- W2136993618 hasRelatedWork W2035249001 @default.
- W2136993618 hasRelatedWork W2066766634 @default.
- W2136993618 hasRelatedWork W2089460504 @default.
- W2136993618 hasRelatedWork W2136993618 @default.
- W2136993618 hasRelatedWork W2260717474 @default.
- W2136993618 hasRelatedWork W337990198 @default.
- W2136993618 hasVolume "70" @default.
- W2136993618 isParatext "false" @default.
- W2136993618 isRetracted "false" @default.
- W2136993618 magId "2136993618" @default.
- W2136993618 workType "article" @default.