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- W2137004080 abstract "<b>Background:</b> C reactive protein (CRP) is a known indicator of inflammation. Serum CRP is often raised in patients with inflammatory conditions. <b>Objective:</b> To determine whether individuals make antibodies to CRP and whether this might affect serum CRP concentrations. <b>Methods:</b> An enzyme linked immunosorbent assay was developed for the detection of antibodies to CRP. Specificity of the reaction was determined by inhibition of the reaction. <b>Results:</b> Sera from 413 patients were tested and 25 were found to be positive, particularly in patients with rheumatic diseases. Levels of anti-CRP did not correlate with serum CRP levels. <b>Conclusions:</b> The presence of low CRP levels may not reflect the presence of antibodies to CRP." @default.
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- W2137004080 date "2006-05-01" @default.
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- W2137004080 title "Antibodies to C reactive protein" @default.
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- W2137004080 doi "https://doi.org/10.1136/ard.2005.037895" @default.
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