FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137030280> ?p ?o ?g. }

• W2137030280 abstract "Genetic polymophisms of the Duffy antigen receptor for the chemokines (DARC) gene successfully protected against blood stage infection by Plasmodium vivax infection. The Fy (a-, b-) phenotype is predominant among African populations, particularly those originating from West Africa, and it is rare among non-African populations. The aim of this study was to analyse the frequency of four Duffy blood groups based on SNPs (T-33C, G125A, G298A and C5411T) in two local tribes of Sudanese Arabs, the Shagia and Manasir, which are both from the region of the Fourth Nile cataract in Sudan. An analysis of polymorphisms was performed on 217 individuals (126 representatives of the Shagia tribe and 91 of the Manasir). Real-time PCR and TaqMan Genotyping Assays were used to study the prevalence of alleles and genotypes. The analysis of allelic and genotype frequency in the T-33C polymorphisms demonstrated a significant dominance of the C allele and CC genotype (OR = 0.53 [0.32-0.88]; p = 0.02) in both tribes. The G125A polymorphism is associated with phenotype Fy(a-, b-) and was identified in 83% of Shagia and 77% of Manasir. With regard to G298A polymorphisms, the genotype frequencies were different between the tribes (p = 0,002) and no single AA homozygote was found. Based on four SNPs examined, 20 combinations of genotypes for the Shagia and Manasir tribes were determined. The genotype CC/AA/GG/CT occurred most often in Shagia tribe (45.9%) but was rare in the Manasir tribe (6.6%) (p < 0.001 Shagia versus Manasir). The FY*A ES allele was identified in both analysed tribes. The presence of individuals with the FY*A/FY*A genotype was demonstrated only in the Shagia tribe. This is probably the first report showing genotypically Duffy-negative people who carry both FY*B ES and FY*A ES . The identification of the FY*A ES allele in both tribes may be due to admixture of the non-African genetic background. Taken as a whole, allele and genotype frequencies between the Shagia and the Manasir were statistically different. However, the presence of individuals with the FY*A/FY*A genotype was demonstrated only in the Shagia tribe." @default.
• W2137030280 created "2016-06-24" @default.
• W2137030280 creator A5001859689 @default.
• W2137030280 creator A5009113410 @default.
• W2137030280 creator A5012919609 @default.
• W2137030280 creator A5028199217 @default.
• W2137030280 creator A5062342520 @default.
• W2137030280 creator A5081636541 @default.
• W2137030280 creator A5083109686 @default.
• W2137030280 date "2012-04-17" @default.
• W2137030280 modified "2023-10-12" @default.
• W2137030280 title "Analysis for genotyping Duffy blood group in inhabitants of Sudan, the Fourth Cataract of the Nile" @default.
• W2137030280 cites W10853290 @default.
• W2137030280 cites W1556057348 @default.
• W2137030280 cites W162264688 @default.
• W2137030280 cites W1978433253 @default.
• W2137030280 cites W1980876585 @default.
• W2137030280 cites W1985830698 @default.
• W2137030280 cites W1987689008 @default.
• W2137030280 cites W1998197559 @default.
• W2137030280 cites W2013406397 @default.
• W2137030280 cites W2016965182 @default.
• W2137030280 cites W2019926473 @default.
• W2137030280 cites W2038204679 @default.
• W2137030280 cites W2038237784 @default.
• W2137030280 cites W2039321105 @default.
• W2137030280 cites W2043743064 @default.
• W2137030280 cites W2053671079 @default.
• W2137030280 cites W2062735402 @default.
• W2137030280 cites W2071989354 @default.
• W2137030280 cites W2080491517 @default.
• W2137030280 cites W2083169658 @default.
• W2137030280 cites W2089668941 @default.
• W2137030280 cites W2090430326 @default.
• W2137030280 cites W2099466163 @default.
• W2137030280 cites W2108117056 @default.
• W2137030280 cites W2127695879 @default.
• W2137030280 cites W2129316818 @default.
• W2137030280 cites W2130799876 @default.
• W2137030280 cites W2132497218 @default.
• W2137030280 cites W2140026462 @default.
• W2137030280 cites W2140460887 @default.
• W2137030280 cites W2145404883 @default.
• W2137030280 cites W2153495843 @default.
• W2137030280 cites W2157182804 @default.
• W2137030280 cites W2166614971 @default.
• W2137030280 cites W2168976934 @default.
• W2137030280 doi "https://doi.org/10.1186/1475-2875-11-115" @default.
• W2137030280 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3375187" @default.
• W2137030280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22510366" @default.
• W2137030280 hasPublicationYear "2012" @default.
• W2137030280 type Work @default.
• W2137030280 sameAs 2137030280 @default.
• W2137030280 citedByCount "22" @default.
• W2137030280 countsByYear W21370302802012 @default.
• W2137030280 countsByYear W21370302802013 @default.
• W2137030280 countsByYear W21370302802014 @default.
• W2137030280 countsByYear W21370302802015 @default.
• W2137030280 countsByYear W21370302802016 @default.
• W2137030280 countsByYear W21370302802017 @default.
• W2137030280 countsByYear W21370302802018 @default.
• W2137030280 countsByYear W21370302802019 @default.
• W2137030280 countsByYear W21370302802020 @default.
• W2137030280 countsByYear W21370302802022 @default.
• W2137030280 countsByYear W21370302802023 @default.
• W2137030280 crossrefType "journal-article" @default.
• W2137030280 hasAuthorship W2137030280A5001859689 @default.
• W2137030280 hasAuthorship W2137030280A5009113410 @default.
• W2137030280 hasAuthorship W2137030280A5012919609 @default.
• W2137030280 hasAuthorship W2137030280A5028199217 @default.
• W2137030280 hasAuthorship W2137030280A5062342520 @default.
• W2137030280 hasAuthorship W2137030280A5081636541 @default.
• W2137030280 hasAuthorship W2137030280A5083109686 @default.
• W2137030280 hasBestOaLocation W21370302801 @default.
• W2137030280 hasConcept C104317684 @default.
• W2137030280 hasConcept C135763542 @default.
• W2137030280 hasConcept C144024400 @default.
• W2137030280 hasConcept C151913843 @default.
• W2137030280 hasConcept C153209595 @default.
• W2137030280 hasConcept C159047783 @default.
• W2137030280 hasConcept C180754005 @default.
• W2137030280 hasConcept C19165224 @default.
• W2137030280 hasConcept C203014093 @default.
• W2137030280 hasConcept C2779121571 @default.
• W2137030280 hasConcept C31467283 @default.
• W2137030280 hasConcept C37463918 @default.
• W2137030280 hasConcept C54355233 @default.
• W2137030280 hasConcept C86803240 @default.
• W2137030280 hasConceptScore W2137030280C104317684 @default.
• W2137030280 hasConceptScore W2137030280C135763542 @default.
• W2137030280 hasConceptScore W2137030280C144024400 @default.
• W2137030280 hasConceptScore W2137030280C151913843 @default.
• W2137030280 hasConceptScore W2137030280C153209595 @default.
• W2137030280 hasConceptScore W2137030280C159047783 @default.
• W2137030280 hasConceptScore W2137030280C180754005 @default.
• W2137030280 hasConceptScore W2137030280C19165224 @default.
• W2137030280 hasConceptScore W2137030280C203014093 @default.
• W2137030280 hasConceptScore W2137030280C2779121571 @default.
• W2137030280 hasConceptScore W2137030280C31467283 @default.
• W2137030280 hasConceptScore W2137030280C37463918 @default.

• next