Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137115293> ?p ?o ?g. }
- W2137115293 endingPage "9827" @default.
- W2137115293 startingPage "9819" @default.
- W2137115293 abstract "Dynein is a minus-end-directed microtubule-associated motor protein involved in cargo transport in the cytoplasm. African swine fever virus (ASFV), a large DNA virus, hijacks the microtubule motor complex cellular transport machinery during virus infection of the cell through direct binding of virus protein p54 to the light chain of cytoplasmic dynein (LC8). Interaction of p54 and LC8 occurs both in vitro and in cells, and the two proteins colocalize at the microtubular organizing center during viral infection. p50/dynamitin, a dominant-negative inhibitor of dynein-dynactin function, impeded ASFV infection, suggesting an essential role for dynein during virus infection. A 13-amino-acid domain of p54 was sufficient for binding to LC8, an SQT motif within this domain being critical for this binding. Direct binding of a viral structural protein to LC8, a small molecule of the dynein motor complex, could constitute a molecular mechanism for microtubule-mediated virus transport." @default.
- W2137115293 created "2016-06-24" @default.
- W2137115293 creator A5007364208 @default.
- W2137115293 creator A5025086154 @default.
- W2137115293 creator A5026998248 @default.
- W2137115293 creator A5051669449 @default.
- W2137115293 creator A5065356926 @default.
- W2137115293 creator A5069797124 @default.
- W2137115293 creator A5070298321 @default.
- W2137115293 creator A5075195856 @default.
- W2137115293 creator A5075936386 @default.
- W2137115293 date "2001-10-15" @default.
- W2137115293 modified "2023-10-01" @default.
- W2137115293 title "African Swine Fever Virus Protein p54 Interacts with the Microtubular Motor Complex through Direct Binding to Light-Chain Dynein" @default.
- W2137115293 cites W1515549973 @default.
- W2137115293 cites W1545152378 @default.
- W2137115293 cites W1568040350 @default.
- W2137115293 cites W1822348693 @default.
- W2137115293 cites W1857660355 @default.
- W2137115293 cites W1876993892 @default.
- W2137115293 cites W1964016573 @default.
- W2137115293 cites W1969548298 @default.
- W2137115293 cites W1971194337 @default.
- W2137115293 cites W1974947944 @default.
- W2137115293 cites W1975369327 @default.
- W2137115293 cites W1976822357 @default.
- W2137115293 cites W1977186059 @default.
- W2137115293 cites W1978811057 @default.
- W2137115293 cites W1981166298 @default.
- W2137115293 cites W1985151525 @default.
- W2137115293 cites W1992203354 @default.
- W2137115293 cites W1995438935 @default.
- W2137115293 cites W2012401859 @default.
- W2137115293 cites W2012660700 @default.
- W2137115293 cites W2014971990 @default.
- W2137115293 cites W2020481660 @default.
- W2137115293 cites W2025129187 @default.
- W2137115293 cites W2033034912 @default.
- W2137115293 cites W2040116591 @default.
- W2137115293 cites W2046928671 @default.
- W2137115293 cites W2050126429 @default.
- W2137115293 cites W2053242433 @default.
- W2137115293 cites W2060321011 @default.
- W2137115293 cites W2062840171 @default.
- W2137115293 cites W2072170340 @default.
- W2137115293 cites W2072950542 @default.
- W2137115293 cites W2077563423 @default.
- W2137115293 cites W2077686137 @default.
- W2137115293 cites W2083920837 @default.
- W2137115293 cites W2087599118 @default.
- W2137115293 cites W2092923090 @default.
- W2137115293 cites W2094017503 @default.
- W2137115293 cites W2094529805 @default.
- W2137115293 cites W2095056537 @default.
- W2137115293 cites W2103617829 @default.
- W2137115293 cites W2105995626 @default.
- W2137115293 cites W2109975756 @default.
- W2137115293 cites W2120533372 @default.
- W2137115293 cites W2122806729 @default.
- W2137115293 cites W2125453887 @default.
- W2137115293 cites W2127868482 @default.
- W2137115293 cites W2131544701 @default.
- W2137115293 cites W2134964586 @default.
- W2137115293 cites W2139741312 @default.
- W2137115293 cites W2141136492 @default.
- W2137115293 cites W2141372231 @default.
- W2137115293 cites W2143764490 @default.
- W2137115293 cites W2147890616 @default.
- W2137115293 cites W2162530599 @default.
- W2137115293 cites W2162976896 @default.
- W2137115293 cites W2163643581 @default.
- W2137115293 cites W2168760539 @default.
- W2137115293 cites W2180626799 @default.
- W2137115293 cites W4236734836 @default.
- W2137115293 cites W81882322 @default.
- W2137115293 doi "https://doi.org/10.1128/jvi.75.20.9819-9827.2001" @default.
- W2137115293 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/114554" @default.
- W2137115293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11559815" @default.
- W2137115293 hasPublicationYear "2001" @default.
- W2137115293 type Work @default.
- W2137115293 sameAs 2137115293 @default.
- W2137115293 citedByCount "167" @default.
- W2137115293 countsByYear W21371152932012 @default.
- W2137115293 countsByYear W21371152932013 @default.
- W2137115293 countsByYear W21371152932014 @default.
- W2137115293 countsByYear W21371152932015 @default.
- W2137115293 countsByYear W21371152932016 @default.
- W2137115293 countsByYear W21371152932017 @default.
- W2137115293 countsByYear W21371152932018 @default.
- W2137115293 countsByYear W21371152932019 @default.
- W2137115293 countsByYear W21371152932020 @default.
- W2137115293 countsByYear W21371152932021 @default.
- W2137115293 countsByYear W21371152932022 @default.
- W2137115293 countsByYear W21371152932023 @default.
- W2137115293 crossrefType "journal-article" @default.
- W2137115293 hasAuthorship W2137115293A5007364208 @default.
- W2137115293 hasAuthorship W2137115293A5025086154 @default.
- W2137115293 hasAuthorship W2137115293A5026998248 @default.