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- W2137128950 abstract "Objective: We examined the relationships between long‐term treatment response, side‐effects and drug discontinuation in panic disorder (PD)–agoraphobia. Method: A total of 326 patients were naturalistically treated with antidepressants and followed for a period of 3 years. All patients were evaluated by means of the Panic Disorder/Agoraphobia Interview and the Longitudinal Interview Follow‐up Examination (LIFE‐UP). Results: A total of 179 patients interrupted pharmacological treatment. Among them, 26.8% were not traceable; 36.9% had deemed further contact with the psychiatrist unnecessary because of remission. Other reasons for interruption were: ineffectiveness (18.4%), side‐effects (10.6%) and personal reasons (7.3%). Patients who interrupted pharmacological treatment because of symptom remission remained in the study for a longer period than those patients who interrupted their treatment because of inefficacy. Conclusion: In the long‐term treatment of PD with antidepressants, a high percentage of patients who have achieved symptom remission tend to default from further treatment; adherence to long‐term treatment with antidepressants was predicted by severe and long‐lasting symptomatology." @default.
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- W2137128950 date "2004-07-05" @default.
- W2137128950 modified "2023-10-17" @default.
- W2137128950 title "Spontaneous treatment discontinuation in panic disorder patients treated with antidepressants" @default.
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- W2137128950 doi "https://doi.org/10.1111/j.1600-0047.2004.00347.x" @default.
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