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- W2137129162 abstract "Spleen cells from congenitally athymic (“nude”) mice were found to give a good anti-hapten response when cultured with the hapten-carrier, dinitrophenyl (DNP)-flagellin, but not when cultured with DNP coupled to two other proteins, hemocyanin and human IgG. This response to DNP-flagellin was anti-theta-sensitive. The evidence indicated that the mice had a small population of T cells, a proportion of which had become primed naturally to flagellin or to related antigens and could function as specific helper cells in a collaborative anti-DNP response. The existence of such flagellin-primed T cells was confirmed by the ability of such mice to mount a delayed type hypersensitivity reaction to flagellin injected into the hind footpad." @default.
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- W2137129162 date "1974-11-01" @default.
- W2137129162 modified "2023-09-25" @default.
- W2137129162 title "An anti-theta sensitive hapten-carrier response in nude mice" @default.
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- W2137129162 doi "https://doi.org/10.1002/eji.1830041107" @default.
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