Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137133485> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2137133485 endingPage "73" @default.
- W2137133485 startingPage "70" @default.
- W2137133485 abstract "OBJECTIVE To report the development of nephrogenic diabetes insipidus (NDI) associated with the use of high-dose liposomal amphotericin B. CASE SUMMARY A 38-year-old white man with relapsed acute myelogenous leukemia underwent a matched unrelated donor allogeneic bone marrow transplant with adequate engraftment and mild graft-versus–host disease responding to corticosteroids. Approximately 11 months after transplant, the patient was admitted to the hospital with suspected fungal pneumonia and started on liposomal amphotericin B (baseline serum creatinine 1.4–1.5 mg/dL). The dose was increased due to his immunosuppression and poor response, as the fungal etiology was identified as Torulopsis glabrata. The patient required mechanical ventilation due to biopsy-proven bronchiolitis olbiterans organizing pneumonia. Additionally, he developed diffuse alveolar hemorrhage and received intravenous desmopressin, with a reduction in bloody secretions. He also developed hypernatremia (serum sodium 155 mEq/L) on day 3 of the desmopressin and had an inappropriately increased urine output consistent with NDI. The most likely etiology for the NDI was liposomal amphotericin B and its associated hypokalemia. DISCUSSION The observation of worsening hypernatremia (serum sodium increased from 135 to 164 mEq/L) with polyuria was associated with an increasing cumulative dosage of liposomal amphotericin B for fungal pneumonia despite the concurrent use of intravenous desmopressin. Aggressive water replacement was an effective treatment option in this patient. The Naranjo probability scale classified this as a possible adverse reaction because of the temporal sequence of NDI after high-dose liposomal amphotericin B and previously reported cases of NDI associated with amphotericin B desoxycholate. CONCLUSIONS Amphotericin B desoxycholate has been implicated as an etiology for NDI, and the use of the newer liposomal amphotericin B reportedly avoids this rare complication. We observed the development of NDI despite the use of liposomal amphotericin B in a critically ill patient with bone marrow transplant." @default.
- W2137133485 created "2016-06-24" @default.
- W2137133485 creator A5035395876 @default.
- W2137133485 creator A5037434567 @default.
- W2137133485 creator A5084835586 @default.
- W2137133485 date "2003-01-01" @default.
- W2137133485 modified "2023-10-16" @default.
- W2137133485 title "Possible Liposomal Amphotericin B–Induced Nephrogenic Diabetes Insipidus" @default.
- W2137133485 cites W2021859325 @default.
- W2137133485 cites W2031902635 @default.
- W2137133485 cites W2032377473 @default.
- W2137133485 cites W2067978628 @default.
- W2137133485 cites W2081279508 @default.
- W2137133485 cites W2083068862 @default.
- W2137133485 cites W2086156479 @default.
- W2137133485 cites W2114471058 @default.
- W2137133485 cites W2140385941 @default.
- W2137133485 cites W2166858780 @default.
- W2137133485 cites W4251335395 @default.
- W2137133485 cites W43291129 @default.
- W2137133485 doi "https://doi.org/10.1345/aph.1c204" @default.
- W2137133485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12503936" @default.
- W2137133485 hasPublicationYear "2003" @default.
- W2137133485 type Work @default.
- W2137133485 sameAs 2137133485 @default.
- W2137133485 citedByCount "13" @default.
- W2137133485 countsByYear W21371334852015 @default.
- W2137133485 crossrefType "journal-article" @default.
- W2137133485 hasAuthorship W2137133485A5035395876 @default.
- W2137133485 hasAuthorship W2137133485A5037434567 @default.
- W2137133485 hasAuthorship W2137133485A5084835586 @default.
- W2137133485 hasConcept C126322002 @default.
- W2137133485 hasConcept C141071460 @default.
- W2137133485 hasConcept C16005928 @default.
- W2137133485 hasConcept C178790620 @default.
- W2137133485 hasConcept C185592680 @default.
- W2137133485 hasConcept C2776958162 @default.
- W2137133485 hasConcept C2777464133 @default.
- W2137133485 hasConcept C2777914695 @default.
- W2137133485 hasConcept C2778242168 @default.
- W2137133485 hasConcept C2778702241 @default.
- W2137133485 hasConcept C2778864100 @default.
- W2137133485 hasConcept C2779548794 @default.
- W2137133485 hasConcept C2779629538 @default.
- W2137133485 hasConcept C537181965 @default.
- W2137133485 hasConcept C71924100 @default.
- W2137133485 hasConcept C90924648 @default.
- W2137133485 hasConceptScore W2137133485C126322002 @default.
- W2137133485 hasConceptScore W2137133485C141071460 @default.
- W2137133485 hasConceptScore W2137133485C16005928 @default.
- W2137133485 hasConceptScore W2137133485C178790620 @default.
- W2137133485 hasConceptScore W2137133485C185592680 @default.
- W2137133485 hasConceptScore W2137133485C2776958162 @default.
- W2137133485 hasConceptScore W2137133485C2777464133 @default.
- W2137133485 hasConceptScore W2137133485C2777914695 @default.
- W2137133485 hasConceptScore W2137133485C2778242168 @default.
- W2137133485 hasConceptScore W2137133485C2778702241 @default.
- W2137133485 hasConceptScore W2137133485C2778864100 @default.
- W2137133485 hasConceptScore W2137133485C2779548794 @default.
- W2137133485 hasConceptScore W2137133485C2779629538 @default.
- W2137133485 hasConceptScore W2137133485C537181965 @default.
- W2137133485 hasConceptScore W2137133485C71924100 @default.
- W2137133485 hasConceptScore W2137133485C90924648 @default.
- W2137133485 hasIssue "1" @default.
- W2137133485 hasLocation W21371334851 @default.
- W2137133485 hasLocation W21371334852 @default.
- W2137133485 hasOpenAccess W2137133485 @default.
- W2137133485 hasPrimaryLocation W21371334851 @default.
- W2137133485 hasRelatedWork W2034793767 @default.
- W2137133485 hasRelatedWork W2054182134 @default.
- W2137133485 hasRelatedWork W2249377240 @default.
- W2137133485 hasRelatedWork W2394623540 @default.
- W2137133485 hasRelatedWork W2442394313 @default.
- W2137133485 hasRelatedWork W2730801642 @default.
- W2137133485 hasRelatedWork W283784031 @default.
- W2137133485 hasRelatedWork W2936345030 @default.
- W2137133485 hasRelatedWork W3197060261 @default.
- W2137133485 hasRelatedWork W4367848039 @default.
- W2137133485 hasVolume "37" @default.
- W2137133485 isParatext "false" @default.
- W2137133485 isRetracted "false" @default.
- W2137133485 magId "2137133485" @default.
- W2137133485 workType "article" @default.