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- W2137162349 abstract "Together with tRNACUAPyl, a rationally designed pyrrolysyl-tRNA synthetase mutant N346A/C348A has been successfully used for the genetic incorporation of a variety of phenylalanine derivatives with large para substituents into superfolder green fluorescent protein at an amber mutation site in Escherichia coli. This discovery greatly expands the genetically encoded noncanonical amino acid inventory and opens the gate for the genetic incorporation of other phenylalanine derivatives using engineered pyrrolysyl-tRNA synthetase-tRNACUAPyl pairs." @default.
- W2137162349 created "2016-06-24" @default.
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- W2137162349 date "2012-02-06" @default.
- W2137162349 modified "2023-10-16" @default.
- W2137162349 title "A Rationally Designed Pyrrolysyl-tRNA Synthetase Mutant with a Broad Substrate Spectrum" @default.
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- W2137162349 doi "https://doi.org/10.1021/ja211972x" @default.
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