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• W2137168087 startingPage "e34397" @default.
• W2137168087 abstract "Despite the popularity of zebrafish as a research model, its sex determination (SD) mechanism is still unknown. Most cytogenetic studies failed to find dimorphic sex chromosomes and no primary sex determining switch has been identified even though the assembly of zebrafish genome sequence is near to completion and a high resolution genetic map is available. Recent publications suggest that environmental factors within the natural range have minimal impact on sex ratios of zebrafish populations. The primary aim of this study is to find out more about how sex is determined in zebrafish.Using classical breeding experiments, we found that sex ratios across families were wide ranging (4.8% to 97.3% males). On the other hand, repeated single pair crossings produced broods of very similar sex ratios, indicating that parental genotypes have a role in the sex ratio of the offspring. Variation among family sex ratios was reduced after selection for breeding pairs with predominantly male or female offspring, another indication that zebrafish sex is regulated genetically. Further examinations by a PCR-based blind assay and array comparative genomic hybridization both failed to find universal sex-linked differences between the male and female genomes. Together with the ability to increase the sex bias of lines by selective breeding, these data suggest that zebrafish is unlikely to utilize a chromosomal sex determination (CSD) system.Taken together, our study suggests that zebrafish sex is genetically determined with limited, secondary influences from the environment. As we have not found any sign for CSD in the species, we propose that the zebrafish has a polygenic sex determination system." @default.
• W2137168087 created "2016-06-24" @default.
• W2137168087 creator A5001370177 @default.
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• W2137168087 date "2012-04-10" @default.
• W2137168087 modified "2023-10-16" @default.
• W2137168087 title "Polygenic Sex Determination System in Zebrafish" @default.
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• W2137168087 cites W1511446312 @default.
• W2137168087 cites W1590652203 @default.
• W2137168087 cites W1606142379 @default.
• W2137168087 cites W1963953102 @default.
• W2137168087 cites W1968896842 @default.
• W2137168087 cites W1972788206 @default.
• W2137168087 cites W1974572893 @default.
• W2137168087 cites W1978529094 @default.
• W2137168087 cites W1981223502 @default.
• W2137168087 cites W1986886445 @default.
• W2137168087 cites W1996689072 @default.
• W2137168087 cites W1997551492 @default.
• W2137168087 cites W1999102617 @default.
• W2137168087 cites W2002758933 @default.
• W2137168087 cites W2003706184 @default.
• W2137168087 cites W2004541293 @default.
• W2137168087 cites W2011791666 @default.
• W2137168087 cites W2012736441 @default.
• W2137168087 cites W2014012238 @default.
• W2137168087 cites W2017784553 @default.
• W2137168087 cites W2018618597 @default.
• W2137168087 cites W2021714239 @default.
• W2137168087 cites W2022980475 @default.
• W2137168087 cites W2026125991 @default.
• W2137168087 cites W2027648691 @default.
• W2137168087 cites W2028079118 @default.
• W2137168087 cites W2030676023 @default.
• W2137168087 cites W2032916497 @default.
• W2137168087 cites W2036700061 @default.
• W2137168087 cites W2037882068 @default.
• W2137168087 cites W2047641515 @default.
• W2137168087 cites W2052824268 @default.
• W2137168087 cites W2064086951 @default.
• W2137168087 cites W2064202975 @default.
• W2137168087 cites W2069158758 @default.
• W2137168087 cites W2077560413 @default.
• W2137168087 cites W2077659086 @default.
• W2137168087 cites W2078637907 @default.
• W2137168087 cites W2081389560 @default.
• W2137168087 cites W2083928363 @default.
• W2137168087 cites W2091385113 @default.
• W2137168087 cites W2094523329 @default.
• W2137168087 cites W2097062585 @default.
• W2137168087 cites W2102190537 @default.
• W2137168087 cites W2102706241 @default.
• W2137168087 cites W2103559458 @default.
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• W2137168087 cites W2126068923 @default.
• W2137168087 cites W2126814743 @default.
• W2137168087 cites W2131347141 @default.
• W2137168087 cites W2142069354 @default.
• W2137168087 cites W2147190637 @default.
• W2137168087 cites W2148229753 @default.
• W2137168087 cites W2148393949 @default.
• W2137168087 cites W2155707112 @default.
• W2137168087 cites W2157758516 @default.
• W2137168087 cites W2159552369 @default.
• W2137168087 cites W2160756774 @default.
• W2137168087 cites W2161863335 @default.
• W2137168087 cites W2163735827 @default.
• W2137168087 cites W2167529600 @default.
• W2137168087 cites W2169402180 @default.
• W2137168087 cites W2171114940 @default.
• W2137168087 cites W2171907913 @default.
• W2137168087 cites W2174326952 @default.
• W2137168087 cites W2326050236 @default.
• W2137168087 cites W273323996 @default.
• W2137168087 cites W280813325 @default.
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• W2137168087 doi "https://doi.org/10.1371/journal.pone.0034397" @default.
• W2137168087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3323597" @default.
• W2137168087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22506019" @default.
• W2137168087 hasPublicationYear "2012" @default.
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