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- W2137202472 abstract "This chapter looks at the evidence base for the practice of fetal medicine and surgery. There is very little good-quality research and much activity is based on case reports and series. However, the philosophy of evidence-based practice is now accepted and new randomized trials are being published in the literature (e.g. fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia and laser treatment of the twin-to-twin transfusion syndrome). Many well established techniques would not be suitable for randomized trials but, as new techniques related to established practice are introduced (e.g. middle cerebral artery Doppler assessment), well-designed trials are essential to ensure they are safe, clinically useful and at least as good as standard practice. In this unique area of medicine, where ethical and emotional issues interplay with clinical practice, it is important not to introduce exciting techniques without solid evidence that they are beneficial both in the short and the long term." @default.
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- W2137202472 date "2005-02-01" @default.
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- W2137202472 title "The evidence base for fetal medicine" @default.
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- W2137202472 doi "https://doi.org/10.1016/j.bpobgyn.2004.10.016" @default.
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