FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137328463> ?p ?o ?g. }

• W2137328463 endingPage "1418" @default.
• W2137328463 startingPage "1414" @default.
• W2137328463 abstract "Type II collagen (COL II) is one of the primary components of hyaline cartilage and plays a key role in maintaining chondrocyte function. COL II is the principal target of destruction, and matrix metalloproteases (MMPs) have a major role in arthritis. In the present study, we investigated the chondroctye protection effects of specific fraction of yeast hydrolysate ((10–30 kDa molecular weight peptides). The mRNA expression of COL II was significantly increased in the YH-treated group compared to the control at concentrations above 50 µg/ml, respectively. The 200 µg/ml YH-treated group (3.43 ± 0.23 µg/ml) showed significantly reduced glycosaminoglycan (GAG) degradation relative to that in the interleukin-1β (IL-1β)-treated control group (4.72 ± 0.05 µg/ml). In the YH-treated group, MMP-13 level was significantly decreased in a dose-dependent manner compared to the IL-1β-treated group without YH treatment. However, MMP-1 and MMP-3 level were not different from that of control. Under the same conditions, we also examined mRNA levels of COL II. The mRNA expression of COL II was significantly higher in the YH-treated group than in the IL-1β-treated control group at concentrations above 100 µg/ml. In conclusion, YH stimulated COL II synthesis and significantly inhibited MMP-13 and GAG degradation caused by IL-1β treatment. Copyright © 2012 John Wiley & Sons, Ltd." @default.
• W2137328463 created "2016-06-24" @default.
• W2137328463 creator A5016587342 @default.
• W2137328463 creator A5041669433 @default.
• W2137328463 creator A5063515501 @default.
• W2137328463 creator A5079848254 @default.
• W2137328463 creator A5085614043 @default.
• W2137328463 date "2012-10-16" @default.
• W2137328463 modified "2023-09-26" @default.
• W2137328463 title "Yeast Hydrolysate Protects Cartilage <i>via</i> Stimulation of Type II Collagen Synthesis and Suppression of MMP-13 Production" @default.
• W2137328463 cites W1554947160 @default.
• W2137328463 cites W1882754626 @default.
• W2137328463 cites W1988447859 @default.
• W2137328463 cites W1992645663 @default.
• W2137328463 cites W2005037358 @default.
• W2137328463 cites W2026742987 @default.
• W2137328463 cites W2032255522 @default.
• W2137328463 cites W2033701197 @default.
• W2137328463 cites W2041327426 @default.
• W2137328463 cites W2045005706 @default.
• W2137328463 cites W2046080398 @default.
• W2137328463 cites W2048889862 @default.
• W2137328463 cites W2055833064 @default.
• W2137328463 cites W2075151081 @default.
• W2137328463 cites W2087193732 @default.
• W2137328463 cites W2095512005 @default.
• W2137328463 cites W2138960046 @default.
• W2137328463 cites W2140456977 @default.
• W2137328463 cites W2142075784 @default.
• W2137328463 cites W2147843797 @default.
• W2137328463 cites W4293247451 @default.
• W2137328463 doi "https://doi.org/10.1002/ptr.4857" @default.
• W2137328463 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23070893" @default.
• W2137328463 hasPublicationYear "2012" @default.
• W2137328463 type Work @default.
• W2137328463 sameAs 2137328463 @default.
• W2137328463 citedByCount "3" @default.
• W2137328463 countsByYear W21373284632014 @default.
• W2137328463 countsByYear W21373284632016 @default.
• W2137328463 countsByYear W21373284632019 @default.
• W2137328463 crossrefType "journal-article" @default.
• W2137328463 hasAuthorship W2137328463A5016587342 @default.
• W2137328463 hasAuthorship W2137328463A5041669433 @default.
• W2137328463 hasAuthorship W2137328463A5063515501 @default.
• W2137328463 hasAuthorship W2137328463A5079848254 @default.
• W2137328463 hasAuthorship W2137328463A5085614043 @default.
• W2137328463 hasConcept C104317684 @default.
• W2137328463 hasConcept C105580179 @default.
• W2137328463 hasConcept C105702510 @default.
• W2137328463 hasConcept C109523444 @default.
• W2137328463 hasConcept C126322002 @default.
• W2137328463 hasConcept C134018914 @default.
• W2137328463 hasConcept C142724271 @default.
• W2137328463 hasConcept C153074725 @default.
• W2137328463 hasConcept C153911025 @default.
• W2137328463 hasConcept C16685009 @default.
• W2137328463 hasConcept C185592680 @default.
• W2137328463 hasConcept C189165786 @default.
• W2137328463 hasConcept C202751555 @default.
• W2137328463 hasConcept C204787440 @default.
• W2137328463 hasConcept C24998067 @default.
• W2137328463 hasConcept C2776164576 @default.
• W2137328463 hasConcept C2777077863 @default.
• W2137328463 hasConcept C2779222958 @default.
• W2137328463 hasConcept C2779335624 @default.
• W2137328463 hasConcept C2780024818 @default.
• W2137328463 hasConcept C2780550940 @default.
• W2137328463 hasConcept C2781013607 @default.
• W2137328463 hasConcept C2781403057 @default.
• W2137328463 hasConcept C28800991 @default.
• W2137328463 hasConcept C3020332539 @default.
• W2137328463 hasConcept C55493867 @default.
• W2137328463 hasConcept C71924100 @default.
• W2137328463 hasConcept C86803240 @default.
• W2137328463 hasConcept C94412978 @default.
• W2137328463 hasConceptScore W2137328463C104317684 @default.
• W2137328463 hasConceptScore W2137328463C105580179 @default.
• W2137328463 hasConceptScore W2137328463C105702510 @default.
• W2137328463 hasConceptScore W2137328463C109523444 @default.
• W2137328463 hasConceptScore W2137328463C126322002 @default.
• W2137328463 hasConceptScore W2137328463C134018914 @default.
• W2137328463 hasConceptScore W2137328463C142724271 @default.
• W2137328463 hasConceptScore W2137328463C153074725 @default.
• W2137328463 hasConceptScore W2137328463C153911025 @default.
• W2137328463 hasConceptScore W2137328463C16685009 @default.
• W2137328463 hasConceptScore W2137328463C185592680 @default.
• W2137328463 hasConceptScore W2137328463C189165786 @default.
• W2137328463 hasConceptScore W2137328463C202751555 @default.
• W2137328463 hasConceptScore W2137328463C204787440 @default.
• W2137328463 hasConceptScore W2137328463C24998067 @default.
• W2137328463 hasConceptScore W2137328463C2776164576 @default.
• W2137328463 hasConceptScore W2137328463C2777077863 @default.
• W2137328463 hasConceptScore W2137328463C2779222958 @default.
• W2137328463 hasConceptScore W2137328463C2779335624 @default.
• W2137328463 hasConceptScore W2137328463C2780024818 @default.
• W2137328463 hasConceptScore W2137328463C2780550940 @default.
• W2137328463 hasConceptScore W2137328463C2781013607 @default.
• W2137328463 hasConceptScore W2137328463C2781403057 @default.

• next