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- W2137410004 abstract "Lotrisone® a topical agent intended for the treatment of cutaneous fungal and yeast infections, is a combination of the broad spectrum antifungal/anticandidal agent clotrimazole and the antiinflammatory corticosteroid betamethasone dipropionate. While the individual ingredients in the formulation have been safely marketed for many years, dermal safety testing of the combination product was considered necessary. The potential of the product to check contact irritation or sensitization reactions or photocontact irritation or sensitization reactions was determined using modifications of standard methodologies. The new combination formulation did not elicit any contact photo-irritant, contact photosensitization, or contact sensitive reactions and was not considered to be any more irritative than controls. Results from predictive tests—where possible-were in agreement with those from clinical experiences." @default.
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- W2137410004 date "1984-01-01" @default.
- W2137410004 modified "2023-09-26" @default.
- W2137410004 title "Dermal Safety Studies and Evaluation of a Clotrimazole/Betamethasone Dipropionate Cream Formumtion" @default.
- W2137410004 cites W2010458564 @default.
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- W2137410004 doi "https://doi.org/10.3109/15569528409036282" @default.
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