Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137458001> ?p ?o ?g. }
- W2137458001 endingPage "iii137" @default.
- W2137458001 startingPage "iii124" @default.
- W2137458001 abstract "There are three distinct areas of cancer management that make bone health in cancer patients of increasing clinical importance. First, bone metastases are common in many solid tumours, notably those arising from the breast, prostate and lung, as well as multiple myeloma, and may cause major morbidity including fractures, severe pain, nerve compression and hypercalcaemia. Through optimum multidisciplinary management of patients with bone metastases, including the use of bone-targeted treatments such as potent bisphosphonates or denosumab, it has been possible to transform the course of advanced cancer for many patients resulting in a major reduction in skeletal complications, reduced bone pain and improved quality of life. Secondly, many of the treatments we use to treat cancer patients have effects on reproductive hormones, which are critical for the maintenance of normal bone remodelling. This endocrine disturbance results in accelerated bone loss and an increased risk of osteoporosis and fractures that can have a significant negative impact on the lives of the rapidly expanding number of long-term cancer survivors. Finally, the bone marrow micro-environment is also intimately involved in the metastatic processes required for cancer dissemination, and there are emerging data showing that, at least in some clinical situations, the use of bone-targeted treatments can reduce metastasis to bone and has potential impact on patient survival." @default.
- W2137458001 created "2016-06-24" @default.
- W2137458001 creator A5005046506 @default.
- W2137458001 creator A5033285318 @default.
- W2137458001 creator A5051980635 @default.
- W2137458001 creator A5053293171 @default.
- W2137458001 creator A5070338465 @default.
- W2137458001 date "2014-09-01" @default.
- W2137458001 modified "2023-10-17" @default.
- W2137458001 title "Bone health in cancer patients: ESMO Clinical Practice Guidelines" @default.
- W2137458001 cites W128568834 @default.
- W2137458001 cites W1530002712 @default.
- W2137458001 cites W1607511023 @default.
- W2137458001 cites W1768011742 @default.
- W2137458001 cites W1906721103 @default.
- W2137458001 cites W1954585625 @default.
- W2137458001 cites W1966063111 @default.
- W2137458001 cites W1970874544 @default.
- W2137458001 cites W1971653725 @default.
- W2137458001 cites W1986151600 @default.
- W2137458001 cites W1986544019 @default.
- W2137458001 cites W1987660792 @default.
- W2137458001 cites W1988303925 @default.
- W2137458001 cites W1992053982 @default.
- W2137458001 cites W1993035292 @default.
- W2137458001 cites W1996589664 @default.
- W2137458001 cites W1997732940 @default.
- W2137458001 cites W2003213153 @default.
- W2137458001 cites W2006131871 @default.
- W2137458001 cites W2006638597 @default.
- W2137458001 cites W2015178646 @default.
- W2137458001 cites W2017845136 @default.
- W2137458001 cites W2024266959 @default.
- W2137458001 cites W2024497659 @default.
- W2137458001 cites W2025707250 @default.
- W2137458001 cites W2028209514 @default.
- W2137458001 cites W2036181578 @default.
- W2137458001 cites W2037218654 @default.
- W2137458001 cites W2046308627 @default.
- W2137458001 cites W2054727157 @default.
- W2137458001 cites W2055844573 @default.
- W2137458001 cites W2061202924 @default.
- W2137458001 cites W2064222904 @default.
- W2137458001 cites W2066699153 @default.
- W2137458001 cites W2071433338 @default.
- W2137458001 cites W2073309188 @default.
- W2137458001 cites W2075167228 @default.
- W2137458001 cites W2077015738 @default.
- W2137458001 cites W2079049237 @default.
- W2137458001 cites W2084460361 @default.
- W2137458001 cites W2087769940 @default.
- W2137458001 cites W2088500774 @default.
- W2137458001 cites W2090832878 @default.
- W2137458001 cites W2100244598 @default.
- W2137458001 cites W2100738529 @default.
- W2137458001 cites W2103011422 @default.
- W2137458001 cites W2103904089 @default.
- W2137458001 cites W2104872826 @default.
- W2137458001 cites W2104923745 @default.
- W2137458001 cites W2107925414 @default.
- W2137458001 cites W2108824619 @default.
- W2137458001 cites W2110707581 @default.
- W2137458001 cites W2110768118 @default.
- W2137458001 cites W2113697838 @default.
- W2137458001 cites W2113701976 @default.
- W2137458001 cites W2115871403 @default.
- W2137458001 cites W2115962082 @default.
- W2137458001 cites W2118694999 @default.
- W2137458001 cites W2119486128 @default.
- W2137458001 cites W2124154997 @default.
- W2137458001 cites W2125014991 @default.
- W2137458001 cites W2126357214 @default.
- W2137458001 cites W2136646477 @default.
- W2137458001 cites W2137265090 @default.
- W2137458001 cites W2137539267 @default.
- W2137458001 cites W2139774670 @default.
- W2137458001 cites W2139860898 @default.
- W2137458001 cites W2140421126 @default.
- W2137458001 cites W2141454098 @default.
- W2137458001 cites W2146217561 @default.
- W2137458001 cites W2146810449 @default.
- W2137458001 cites W2148255833 @default.
- W2137458001 cites W2148833625 @default.
- W2137458001 cites W2149520257 @default.
- W2137458001 cites W2149775776 @default.
- W2137458001 cites W2149876087 @default.
- W2137458001 cites W2150904792 @default.
- W2137458001 cites W2152409486 @default.
- W2137458001 cites W2152554716 @default.
- W2137458001 cites W2153579902 @default.
- W2137458001 cites W2155688313 @default.
- W2137458001 cites W2158786144 @default.
- W2137458001 cites W2161604858 @default.
- W2137458001 cites W2162115101 @default.
- W2137458001 cites W2162514583 @default.
- W2137458001 cites W2163949875 @default.
- W2137458001 cites W2164492215 @default.
- W2137458001 cites W2165011173 @default.