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- W2137492047 abstract "Abstract Motivation: Protein–protein interaction networks provide insights into the relationships between the proteins of an organism thereby contributing to a better understanding of cellular processes. Nevertheless, large-scale interaction networks are available for only a few model organisms. Thus, interologs are useful for a systematic transfer of protein interaction networks between organisms. However, no standard tool is available so far for that purpose. Results: In this study, we present an automated prediction tool developed for all sequenced genomes available in Integr8. We also have developed a second method to predict protein–protein interactions in the widely used cyanobacterium Synechocystis. Using these methods, we have constructed a new network of 8783 inferred interactions for Synechocystis. Availability: InteroPORC is open-source, downloadable and usable through a web interface at http://biodev.extra.cea.fr/interoporc/ Contact: michaut.bioinfo@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online." @default.
- W2137492047 created "2016-06-24" @default.
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- W2137492047 date "2008-05-28" @default.
- W2137492047 modified "2023-10-17" @default.
- W2137492047 title "InteroPORC: automated inference of highly conserved protein interaction networks" @default.
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- W2137492047 doi "https://doi.org/10.1093/bioinformatics/btn249" @default.
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