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- W2137571174 abstract "The present study was undertaken to evaluate the immune response after foot and mouth (FMD) disease vaccination at different time interval and also to establish a vaccination schedule against FMD in yak. An oil adjuvanted binary ethylenimine inactivated trivalent FMD vaccine containing virus types O, A and Asia-1 were used in the present study and the vaccine was administered as per the manufacturer‘s recommended dose and route. Antibody response was evaluated using liquid phase blocking ELISA. Eighteen numbers of yaks (6 month to 2 years of age) were divided into three groups viz. groups I, II and III comprising of 6 animals in each group. All the animals of groups I, II and III received the primary dose of vaccine on first day (‘0’ day). The animals of group I and II were given booster dose after one month and two month of primary vaccination respectively and were revaccinated after six month of booster vaccination. Whilst animals of group III were revaccinated after six months of primary vaccination without giving booster dose. The serum samples were collected on the day of vaccination (‘0’ day, prior to vaccination) and thereafter at 30th, 60th, 90th, 120th ,150th ,180th, 210th, 240th and 270th days post primary vaccination (dppv) from all the groups.The animals of group II, showed high level of protective antibody titre to vaccination which persisted up to the next revaccination period that is 240 days post primary vaccination (six month after booster vaccination), whilst none of the animals of group I and III showed antibody titre above protective level to the next revaccination period that is 210 dppv (days post primary vaccination) and 180 dppv respectively. With oil adjuvanted inactivated trivalent FMD vaccine, a booster dose at 60 day post primary vaccination is more effective in yaks which were not vaccinated earlier to maintain protective antibody levels against FMD for a longer duration." @default.
- W2137571174 created "2016-06-24" @default.
- W2137571174 creator A5014046607 @default.
- W2137571174 date "2010-08-17" @default.
- W2137571174 modified "2023-09-27" @default.
- W2137571174 title "Evaluation of immune responses of yak after foot and mouth disease vaccination at different time interval" @default.
- W2137571174 hasPublicationYear "2010" @default.
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