Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137579141> ?p ?o ?g. }
- W2137579141 endingPage "10743" @default.
- W2137579141 startingPage "10738" @default.
- W2137579141 abstract "Signaling pathways essential for axon regeneration, but not for neuron development or function, are particularly well suited targets for therapeutic intervention. We find that the parallel PMK-3(p38) and KGB-1(JNK) MAPK pathways must be coordinately activated to promote axon regeneration. Axon regeneration fails if the activity of either pathway is absent. These two MAPKs are coregulated by the E3 ubiquitin ligase RPM-1(Phr1) via targeted degradation of the MAPKKKs DLK-1 and MLK-1 and by the MAPK phosphatase VHP-1(MKP7), which negatively regulates both PMK-3(p38) and KGB-1(JNK)." @default.
- W2137579141 created "2016-06-24" @default.
- W2137579141 creator A5029913526 @default.
- W2137579141 creator A5039144024 @default.
- W2137579141 creator A5044516003 @default.
- W2137579141 creator A5065759294 @default.
- W2137579141 date "2011-06-13" @default.
- W2137579141 modified "2023-10-09" @default.
- W2137579141 title "Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways" @default.
- W2137579141 cites W1581412826 @default.
- W2137579141 cites W1968195620 @default.
- W2137579141 cites W1973115447 @default.
- W2137579141 cites W1977136440 @default.
- W2137579141 cites W1983712592 @default.
- W2137579141 cites W1986279004 @default.
- W2137579141 cites W1992900501 @default.
- W2137579141 cites W1993366467 @default.
- W2137579141 cites W1996405087 @default.
- W2137579141 cites W2004285818 @default.
- W2137579141 cites W2006227936 @default.
- W2137579141 cites W2006286340 @default.
- W2137579141 cites W2013035816 @default.
- W2137579141 cites W2013500926 @default.
- W2137579141 cites W2017688356 @default.
- W2137579141 cites W2022369108 @default.
- W2137579141 cites W2023904562 @default.
- W2137579141 cites W2027504059 @default.
- W2137579141 cites W2029630756 @default.
- W2137579141 cites W2040131810 @default.
- W2137579141 cites W2045395146 @default.
- W2137579141 cites W2046141144 @default.
- W2137579141 cites W2052935966 @default.
- W2137579141 cites W2054548538 @default.
- W2137579141 cites W2055584891 @default.
- W2137579141 cites W2057807041 @default.
- W2137579141 cites W2058116209 @default.
- W2137579141 cites W2060376582 @default.
- W2137579141 cites W2061104148 @default.
- W2137579141 cites W2061415867 @default.
- W2137579141 cites W2076188357 @default.
- W2137579141 cites W2084472730 @default.
- W2137579141 cites W2091358578 @default.
- W2137579141 cites W2104208969 @default.
- W2137579141 cites W2104968232 @default.
- W2137579141 cites W2109432773 @default.
- W2137579141 cites W2112297277 @default.
- W2137579141 cites W2114638395 @default.
- W2137579141 cites W2132162535 @default.
- W2137579141 cites W2148301289 @default.
- W2137579141 cites W2158021569 @default.
- W2137579141 cites W2324138891 @default.
- W2137579141 cites W2790805946 @default.
- W2137579141 cites W29946730 @default.
- W2137579141 cites W4247333492 @default.
- W2137579141 doi "https://doi.org/10.1073/pnas.1104830108" @default.
- W2137579141 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3127873" @default.
- W2137579141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21670305" @default.
- W2137579141 hasPublicationYear "2011" @default.
- W2137579141 type Work @default.
- W2137579141 sameAs 2137579141 @default.
- W2137579141 citedByCount "176" @default.
- W2137579141 countsByYear W21375791412012 @default.
- W2137579141 countsByYear W21375791412013 @default.
- W2137579141 countsByYear W21375791412014 @default.
- W2137579141 countsByYear W21375791412015 @default.
- W2137579141 countsByYear W21375791412016 @default.
- W2137579141 countsByYear W21375791412017 @default.
- W2137579141 countsByYear W21375791412018 @default.
- W2137579141 countsByYear W21375791412019 @default.
- W2137579141 countsByYear W21375791412020 @default.
- W2137579141 countsByYear W21375791412021 @default.
- W2137579141 countsByYear W21375791412022 @default.
- W2137579141 countsByYear W21375791412023 @default.
- W2137579141 crossrefType "journal-article" @default.
- W2137579141 hasAuthorship W2137579141A5029913526 @default.
- W2137579141 hasAuthorship W2137579141A5039144024 @default.
- W2137579141 hasAuthorship W2137579141A5044516003 @default.
- W2137579141 hasAuthorship W2137579141A5065759294 @default.
- W2137579141 hasBestOaLocation W21375791412 @default.
- W2137579141 hasConcept C104317684 @default.
- W2137579141 hasConcept C11960822 @default.
- W2137579141 hasConcept C134459356 @default.
- W2137579141 hasConcept C171056886 @default.
- W2137579141 hasConcept C178666793 @default.
- W2137579141 hasConcept C25602115 @default.
- W2137579141 hasConcept C2779530196 @default.
- W2137579141 hasConcept C51551487 @default.
- W2137579141 hasConcept C55493867 @default.
- W2137579141 hasConcept C57074206 @default.
- W2137579141 hasConcept C62478195 @default.
- W2137579141 hasConcept C86803240 @default.
- W2137579141 hasConcept C95444343 @default.
- W2137579141 hasConceptScore W2137579141C104317684 @default.
- W2137579141 hasConceptScore W2137579141C11960822 @default.
- W2137579141 hasConceptScore W2137579141C134459356 @default.
- W2137579141 hasConceptScore W2137579141C171056886 @default.
- W2137579141 hasConceptScore W2137579141C178666793 @default.
- W2137579141 hasConceptScore W2137579141C25602115 @default.