FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137594135> ?p ?o ?g. }

• W2137594135 endingPage "135" @default.
• W2137594135 startingPage "126" @default.
• W2137594135 abstract "Human antibodies able to bind with high affinity and specificity to numerous targets have been successfully identified from Fab phage display libraries. A key step in the library selection screening process is the early characterization of library isolates in order to determine which of these isolates to pursue further. Here we describe a Biacore assay that allows isolated clones expressed as soluble Fab fragments in E. coli to be screened and ranked based on their affinity against the target. The assay takes advantage of our ability to measure Fab concentrations in crude bacterial extracts in Biacore using very high density Protein A chips. The procedure allows up to 100 clones per week to be screened and permits the identification of a small number of high-affinity Fabs from a large batch obtained following library selection or affinity maturation." @default.
• W2137594135 created "2016-06-24" @default.
• W2137594135 creator A5000514821 @default.
• W2137594135 creator A5005870134 @default.
• W2137594135 creator A5006543521 @default.
• W2137594135 creator A5027359752 @default.
• W2137594135 creator A5032857255 @default.
• W2137594135 creator A5039705321 @default.
• W2137594135 creator A5073919603 @default.
• W2137594135 creator A5083217155 @default.
• W2137594135 date "2006-03-01" @default.
• W2137594135 modified "2023-10-16" @default.
• W2137594135 title "Rapid kinetic-based screening of human Fab fragments" @default.
• W2137594135 cites W1516410466 @default.
• W2137594135 cites W1965197287 @default.
• W2137594135 cites W1973123086 @default.
• W2137594135 cites W1981902013 @default.
• W2137594135 cites W1989963169 @default.
• W2137594135 cites W2003560670 @default.
• W2137594135 cites W2006588375 @default.
• W2137594135 cites W2026189934 @default.
• W2137594135 cites W2036753716 @default.
• W2137594135 cites W2045109515 @default.
• W2137594135 cites W2056295648 @default.
• W2137594135 cites W2093380070 @default.
• W2137594135 cites W2106937142 @default.
• W2137594135 cites W2109844644 @default.
• W2137594135 cites W2115489142 @default.
• W2137594135 cites W2142230632 @default.
• W2137594135 cites W2148043455 @default.
• W2137594135 cites W2156086434 @default.
• W2137594135 doi "https://doi.org/10.1016/j.jim.2006.01.002" @default.
• W2137594135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16481004" @default.
• W2137594135 hasPublicationYear "2006" @default.
• W2137594135 type Work @default.
• W2137594135 sameAs 2137594135 @default.
• W2137594135 citedByCount "25" @default.
• W2137594135 countsByYear W21375941352012 @default.
• W2137594135 countsByYear W21375941352013 @default.
• W2137594135 countsByYear W21375941352014 @default.
• W2137594135 countsByYear W21375941352015 @default.
• W2137594135 countsByYear W21375941352018 @default.
• W2137594135 countsByYear W21375941352021 @default.
• W2137594135 crossrefType "journal-article" @default.
• W2137594135 hasAuthorship W2137594135A5000514821 @default.
• W2137594135 hasAuthorship W2137594135A5005870134 @default.
• W2137594135 hasAuthorship W2137594135A5006543521 @default.
• W2137594135 hasAuthorship W2137594135A5027359752 @default.
• W2137594135 hasAuthorship W2137594135A5032857255 @default.
• W2137594135 hasAuthorship W2137594135A5039705321 @default.
• W2137594135 hasAuthorship W2137594135A5073919603 @default.
• W2137594135 hasAuthorship W2137594135A5083217155 @default.
• W2137594135 hasConcept C104317684 @default.
• W2137594135 hasConcept C153911025 @default.
• W2137594135 hasConcept C154945302 @default.
• W2137594135 hasConcept C159654299 @default.
• W2137594135 hasConcept C167625842 @default.
• W2137594135 hasConcept C179247698 @default.
• W2137594135 hasConcept C181199279 @default.
• W2137594135 hasConcept C185592680 @default.
• W2137594135 hasConcept C186268636 @default.
• W2137594135 hasConcept C2776471321 @default.
• W2137594135 hasConcept C41008148 @default.
• W2137594135 hasConcept C51323132 @default.
• W2137594135 hasConcept C54355233 @default.
• W2137594135 hasConcept C547475151 @default.
• W2137594135 hasConcept C55493867 @default.
• W2137594135 hasConcept C70721500 @default.
• W2137594135 hasConcept C81917197 @default.
• W2137594135 hasConcept C86803240 @default.
• W2137594135 hasConceptScore W2137594135C104317684 @default.
• W2137594135 hasConceptScore W2137594135C153911025 @default.
• W2137594135 hasConceptScore W2137594135C154945302 @default.
• W2137594135 hasConceptScore W2137594135C159654299 @default.
• W2137594135 hasConceptScore W2137594135C167625842 @default.
• W2137594135 hasConceptScore W2137594135C179247698 @default.
• W2137594135 hasConceptScore W2137594135C181199279 @default.
• W2137594135 hasConceptScore W2137594135C185592680 @default.
• W2137594135 hasConceptScore W2137594135C186268636 @default.
• W2137594135 hasConceptScore W2137594135C2776471321 @default.
• W2137594135 hasConceptScore W2137594135C41008148 @default.
• W2137594135 hasConceptScore W2137594135C51323132 @default.
• W2137594135 hasConceptScore W2137594135C54355233 @default.
• W2137594135 hasConceptScore W2137594135C547475151 @default.
• W2137594135 hasConceptScore W2137594135C55493867 @default.
• W2137594135 hasConceptScore W2137594135C70721500 @default.
• W2137594135 hasConceptScore W2137594135C81917197 @default.
• W2137594135 hasConceptScore W2137594135C86803240 @default.
• W2137594135 hasIssue "1-2" @default.
• W2137594135 hasLocation W21375941351 @default.
• W2137594135 hasLocation W21375941352 @default.
• W2137594135 hasOpenAccess W2137594135 @default.
• W2137594135 hasPrimaryLocation W21375941351 @default.
• W2137594135 hasRelatedWork W1983428057 @default.
• W2137594135 hasRelatedWork W2030191834 @default.
• W2137594135 hasRelatedWork W2056056779 @default.
• W2137594135 hasRelatedWork W2124559972 @default.
• W2137594135 hasRelatedWork W2394244334 @default.

• next