Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137617727> ?p ?o ?g. }
- W2137617727 endingPage "8349" @default.
- W2137617727 startingPage "8341" @default.
- W2137617727 abstract "Cell-repelling structures are often required in biosensors, bioelectronics, and drug delivery systems, but the search for satisfactory cell-repelling structures with good biocompatibility and long-term stability is challenging. In this work, two types of quasi-aligned nanowire arrays (QANWA) with different surface chemistry but similar surface topography, namely titanium carbide–carbon core–shell (TiC/C) and titania (TiO2), are fabricated on Ti6Al4V. Both QANWAs inhibit cell adhesion consequently leading to cell apoptosis possibly due to disruption in the adhesion assembly. Other cell functions such as proliferation and differentiation as monitored by extracellular matrix secretion and mineralization are also substantially depressed. The cell-repelling property is related to the nanostructure but independent of the surface chemistry and surface wettability. It is also not related to protein adsorption which is in fact slightly enhanced on the nanowire arrays. The QANWAs can be modified to have a larger loading capacity thereby enhancing the controlled release kinetics in drug delivery applications and to resist protein adsorption resulting in better biosensor performance. This concept which can be readily extended to other types of QANWAs and biomaterials has broad clinical potential." @default.
- W2137617727 created "2016-06-24" @default.
- W2137617727 creator A5014924091 @default.
- W2137617727 creator A5016410321 @default.
- W2137617727 creator A5049854878 @default.
- W2137617727 creator A5054339536 @default.
- W2137617727 creator A5082656873 @default.
- W2137617727 creator A5083284087 @default.
- W2137617727 date "2010-11-01" @default.
- W2137617727 modified "2023-09-23" @default.
- W2137617727 title "Mechanism of cell repellence on quasi-aligned nanowire arrays on Ti alloy" @default.
- W2137617727 cites W1536076226 @default.
- W2137617727 cites W1576773659 @default.
- W2137617727 cites W1590619267 @default.
- W2137617727 cites W1666890712 @default.
- W2137617727 cites W1966211377 @default.
- W2137617727 cites W1973089587 @default.
- W2137617727 cites W1983271466 @default.
- W2137617727 cites W1986225001 @default.
- W2137617727 cites W1991386525 @default.
- W2137617727 cites W1997486807 @default.
- W2137617727 cites W1999843406 @default.
- W2137617727 cites W2004104374 @default.
- W2137617727 cites W2011009826 @default.
- W2137617727 cites W2012293496 @default.
- W2137617727 cites W2012360452 @default.
- W2137617727 cites W2015375564 @default.
- W2137617727 cites W2016611881 @default.
- W2137617727 cites W2024635003 @default.
- W2137617727 cites W2028518884 @default.
- W2137617727 cites W2034888609 @default.
- W2137617727 cites W2037619760 @default.
- W2137617727 cites W2041964092 @default.
- W2137617727 cites W2049587482 @default.
- W2137617727 cites W2050571839 @default.
- W2137617727 cites W2052081749 @default.
- W2137617727 cites W2052647448 @default.
- W2137617727 cites W2073375166 @default.
- W2137617727 cites W2076783705 @default.
- W2137617727 cites W2087000111 @default.
- W2137617727 cites W2102618905 @default.
- W2137617727 cites W2109787888 @default.
- W2137617727 cites W2114991301 @default.
- W2137617727 cites W2116061386 @default.
- W2137617727 cites W2121475792 @default.
- W2137617727 cites W2127952337 @default.
- W2137617727 cites W2132936019 @default.
- W2137617727 cites W2138248037 @default.
- W2137617727 cites W2141075109 @default.
- W2137617727 cites W2142475480 @default.
- W2137617727 cites W2154421213 @default.
- W2137617727 cites W2157366956 @default.
- W2137617727 cites W2168696958 @default.
- W2137617727 cites W2235679284 @default.
- W2137617727 cites W2319409259 @default.
- W2137617727 cites W4213141530 @default.
- W2137617727 doi "https://doi.org/10.1016/j.biomaterials.2010.07.036" @default.
- W2137617727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20667412" @default.
- W2137617727 hasPublicationYear "2010" @default.
- W2137617727 type Work @default.
- W2137617727 sameAs 2137617727 @default.
- W2137617727 citedByCount "49" @default.
- W2137617727 countsByYear W21376177272012 @default.
- W2137617727 countsByYear W21376177272013 @default.
- W2137617727 countsByYear W21376177272014 @default.
- W2137617727 countsByYear W21376177272015 @default.
- W2137617727 countsByYear W21376177272016 @default.
- W2137617727 countsByYear W21376177272017 @default.
- W2137617727 countsByYear W21376177272018 @default.
- W2137617727 countsByYear W21376177272019 @default.
- W2137617727 countsByYear W21376177272020 @default.
- W2137617727 countsByYear W21376177272021 @default.
- W2137617727 countsByYear W21376177272022 @default.
- W2137617727 countsByYear W21376177272023 @default.
- W2137617727 crossrefType "journal-article" @default.
- W2137617727 hasAuthorship W2137617727A5014924091 @default.
- W2137617727 hasAuthorship W2137617727A5016410321 @default.
- W2137617727 hasAuthorship W2137617727A5049854878 @default.
- W2137617727 hasAuthorship W2137617727A5054339536 @default.
- W2137617727 hasAuthorship W2137617727A5082656873 @default.
- W2137617727 hasAuthorship W2137617727A5083284087 @default.
- W2137617727 hasConcept C115537861 @default.
- W2137617727 hasConcept C12554922 @default.
- W2137617727 hasConcept C127413603 @default.
- W2137617727 hasConcept C134514944 @default.
- W2137617727 hasConcept C150394285 @default.
- W2137617727 hasConcept C159985019 @default.
- W2137617727 hasConcept C160756335 @default.
- W2137617727 hasConcept C171250308 @default.
- W2137617727 hasConcept C178790620 @default.
- W2137617727 hasConcept C185592680 @default.
- W2137617727 hasConcept C191897082 @default.
- W2137617727 hasConcept C192562407 @default.
- W2137617727 hasConcept C2777230088 @default.
- W2137617727 hasConcept C2779820397 @default.
- W2137617727 hasConcept C42360764 @default.
- W2137617727 hasConcept C506065880 @default.
- W2137617727 hasConcept C521977710 @default.