Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137637116> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2137637116 endingPage "56" @default.
- W2137637116 startingPage "52" @default.
- W2137637116 abstract "A systematic characterization of genes with unknown function is a key challenge after the sequencing of the human genome and the genomes of many model organisms. High-throughput RNA-interference (RNAi) screenings have become a widely used approach in invertebrate model organisms and also promise to revolutionize cell biology in mammals. Genome-wide RNAi screens in Caenorhabditis elegans and Drosophila, and in a smaller scale in mammalian cells have proven to be a valuable and successful method for the dissection of diverse biological processes. A number of RNAi libraries have become available that rely on different technologies, such as long double-stranded (ds) RNAs, in vitro diced short-interfering (si) RNAs, synthetic siRNAs and short-hairpin (sh) RNAs, which all have specific advantages and disadvantages. In addition, progress in screening technologies and data analysis allows the adaptation of screening methods to analyse more complex cellular processes. This review will summarize strategies in combining genome-scale RNAi libraries, high-throughput screening technologies, integrated high-content data analysis and will discuss future challenges." @default.
- W2137637116 created "2016-06-24" @default.
- W2137637116 creator A5063107984 @default.
- W2137637116 date "2006-02-23" @default.
- W2137637116 modified "2023-09-23" @default.
- W2137637116 title "Cellular phenotyping by RNAi" @default.
- W2137637116 cites W1611419331 @default.
- W2137637116 cites W1647075334 @default.
- W2137637116 cites W1967641913 @default.
- W2137637116 cites W1974482866 @default.
- W2137637116 cites W1977203585 @default.
- W2137637116 cites W1994557554 @default.
- W2137637116 cites W2003507585 @default.
- W2137637116 cites W2006117889 @default.
- W2137637116 cites W2017642141 @default.
- W2137637116 cites W2034569328 @default.
- W2137637116 cites W2038492783 @default.
- W2137637116 cites W2038863154 @default.
- W2137637116 cites W2040640949 @default.
- W2137637116 cites W2048607934 @default.
- W2137637116 cites W2065221771 @default.
- W2137637116 cites W2092828528 @default.
- W2137637116 cites W2100600738 @default.
- W2137637116 cites W2103924961 @default.
- W2137637116 cites W2115228628 @default.
- W2137637116 cites W2118270653 @default.
- W2137637116 cites W2127347661 @default.
- W2137637116 cites W2128491398 @default.
- W2137637116 cites W2133898735 @default.
- W2137637116 cites W2144654038 @default.
- W2137637116 cites W2146388786 @default.
- W2137637116 cites W2153747430 @default.
- W2137637116 cites W2169718128 @default.
- W2137637116 doi "https://doi.org/10.1093/bfgp/ell007" @default.
- W2137637116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16769679" @default.
- W2137637116 hasPublicationYear "2006" @default.
- W2137637116 type Work @default.
- W2137637116 sameAs 2137637116 @default.
- W2137637116 citedByCount "43" @default.
- W2137637116 countsByYear W21376371162012 @default.
- W2137637116 countsByYear W21376371162013 @default.
- W2137637116 countsByYear W21376371162014 @default.
- W2137637116 countsByYear W21376371162020 @default.
- W2137637116 countsByYear W21376371162023 @default.
- W2137637116 crossrefType "journal-article" @default.
- W2137637116 hasAuthorship W2137637116A5063107984 @default.
- W2137637116 hasBestOaLocation W21376371161 @default.
- W2137637116 hasConcept C104317684 @default.
- W2137637116 hasConcept C141231307 @default.
- W2137637116 hasConcept C166703698 @default.
- W2137637116 hasConcept C19843653 @default.
- W2137637116 hasConcept C2778944004 @default.
- W2137637116 hasConcept C54355233 @default.
- W2137637116 hasConcept C67705224 @default.
- W2137637116 hasConcept C70721500 @default.
- W2137637116 hasConcept C86803240 @default.
- W2137637116 hasConceptScore W2137637116C104317684 @default.
- W2137637116 hasConceptScore W2137637116C141231307 @default.
- W2137637116 hasConceptScore W2137637116C166703698 @default.
- W2137637116 hasConceptScore W2137637116C19843653 @default.
- W2137637116 hasConceptScore W2137637116C2778944004 @default.
- W2137637116 hasConceptScore W2137637116C54355233 @default.
- W2137637116 hasConceptScore W2137637116C67705224 @default.
- W2137637116 hasConceptScore W2137637116C70721500 @default.
- W2137637116 hasConceptScore W2137637116C86803240 @default.
- W2137637116 hasIssue "1" @default.
- W2137637116 hasLocation W21376371161 @default.
- W2137637116 hasLocation W21376371162 @default.
- W2137637116 hasLocation W21376371163 @default.
- W2137637116 hasOpenAccess W2137637116 @default.
- W2137637116 hasPrimaryLocation W21376371161 @default.
- W2137637116 hasRelatedWork W1809349505 @default.
- W2137637116 hasRelatedWork W1946787458 @default.
- W2137637116 hasRelatedWork W2038492783 @default.
- W2137637116 hasRelatedWork W2099118635 @default.
- W2137637116 hasRelatedWork W2106231435 @default.
- W2137637116 hasRelatedWork W2125731289 @default.
- W2137637116 hasRelatedWork W2128491398 @default.
- W2137637116 hasRelatedWork W2143463804 @default.
- W2137637116 hasRelatedWork W2157166663 @default.
- W2137637116 hasRelatedWork W2356314753 @default.
- W2137637116 hasVolume "5" @default.
- W2137637116 isParatext "false" @default.
- W2137637116 isRetracted "false" @default.
- W2137637116 magId "2137637116" @default.
- W2137637116 workType "article" @default.