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• W2137652038 startingPage "1354" @default.
• W2137652038 abstract "Ghrelin is an endogenous ligand of the growth hormone secretagogue receptor, and a potent orexigenic agent in human and rodent studies. We hypothesized that ghrelin may play a role in the reduced grazing time in dairy cows receiving supplementary feeds. Fifty-eight Holstein-Friesian (HF) dairy cows of New Zealand (NZ; n = 28) and North American (NA; n = 30) ancestry were provided with unrestricted access to pasture and randomly allocated at calving to either 0, 3, or 6 kg of dry matter concentrates in a 2 × 3 factorial arrangement. Concentrates were offered in equal amounts at each milking. In peak lactation (75 and 79 ± 19.7 d in milk), blood was sampled from all cows prior to the a.m. milking (i.e., baseline) and following 2 h of unrestricted access to fresh pasture after the a.m. milking on 2 consecutive weeks. Daily milk yield and fat, protein, and lactose concentrations were measured on the day of blood sampling. North American cows produced more milk and consumed numerically more pasture than did NZ cows, and NA cows had elevated plasma ghrelin concentrations pre- and postfeeding. A negative association between dry matter intake and postprandial ghrelin concentrations indicated that other controlling factors may be involved. Circulating ghrelin concentrations before feeding were not affected by concentrate supplementation, but increasing supplementation was associated with a linear decline in pasture intake and postprandial ghrelin concentrations. This negative association between concentrate supplementation and plasma ghrelin concentrations offers a potential neuroendocrine basis for the reduced pasture intake when supplements are offered to cows in grazing systems." @default.
• W2137652038 created "2016-06-24" @default.
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• W2137652038 date "2007-03-01" @default.
• W2137652038 modified "2023-10-16" @default.
• W2137652038 title "Concentrate Supplementation Reduces Postprandial Plasma Ghrelin in Grazing Dairy Cows: A Possible Neuroendocrine Basis for Reduced Pasture Intake in Supplemented Cows" @default.
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• W2137652038 doi "https://doi.org/10.3168/jds.s0022-0302(07)71622-3" @default.
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