FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137665534> ?p ?o ?g. }

• W2137665534 endingPage "992" @default.
• W2137665534 startingPage "987" @default.
• W2137665534 abstract "Chagas disease is a zoonosis transmitted to man by blood-sucking triatomine bugs found in the Americas. Triatoma infestans (Klug, 1834) is the main vector of Chagas' disease in Argentina. The control of this illness relies heavily on vector control through the use of insecticide. However, resistance to pyrethroid insecticides associated with ineffective field treatments has been increasingly reported in T. infestans from Argentina and Bolivia. There are few reports on the expression and causes of resistance in eggs of resistant populations, and even fewer studies on insecticide resistance throughout embryonic development. In this study, we explore the biochemical and molecular mechanisms potentially associated with the deltamethrin resistance assessed in the developing eggs of the Argentinean (Campo Largo) and Bolivian (Entre Ríos) T. infestans populations.We found measurable activity of monooxigenases and pyrethroid esterases throughout embryonic development. The pyrethroid esterase activity grew steadily throughout development in all the studied populations and was highest in eggs 12 d old. Mean enzyme activity increased from 13.6 to 16.3 and 22.2 picomol 7-hydroxycoumarin/min (7-OHC) in eggs of 4-, 7-, and 12 d old from the susceptible reference bug colony. Mean activity of resistant populations increased from 16.0 to 25.9 picomol 7-OHC/min in eggs of 4- to 12 d old in Entre Ríos population, and from 15.9 to 28.9 picomol 7-OHC/min in Campo Largo population. Molecular analysis of susceptible and resistant developing eggs detected L1014F mutation in both resistant populations, but no L925I mutation was found in any of the studied populations.Higher esterase activity and L1014F presence justify the resistance to pyrethroid throughout developing eggs of both studied T. infestans populations. The description of resistance profiles including resistance mechanisms involved will allow a rational design of campaigns for the control of Chagas disease transmission." @default.
• W2137665534 created "2016-06-24" @default.
• W2137665534 creator A5003350180 @default.
• W2137665534 creator A5005121219 @default.
• W2137665534 creator A5009994811 @default.
• W2137665534 creator A5010143613 @default.
• W2137665534 creator A5012679226 @default.
• W2137665534 date "2015-06-24" @default.
• W2137665534 modified "2023-10-08" @default.
• W2137665534 title "Examining Mechanisms of Pyrethroid Resistance in Eggs of Two Populations of the Chagas’ Disease Vector<i>Triatoma infestans</i>(Hemiptera: Reduviidae)" @default.
• W2137665534 cites W1965735290 @default.
• W2137665534 cites W2000803102 @default.
• W2137665534 cites W2023361432 @default.
• W2137665534 cites W2031862351 @default.
• W2137665534 cites W2034327117 @default.
• W2137665534 cites W2044864045 @default.
• W2137665534 cites W2084573274 @default.
• W2137665534 cites W2127951379 @default.
• W2137665534 cites W2132147471 @default.
• W2137665534 cites W2157892575 @default.
• W2137665534 cites W2171004970 @default.
• W2137665534 cites W2172108340 @default.
• W2137665534 cites W2176588149 @default.
• W2137665534 cites W4239622355 @default.
• W2137665534 cites W4246281238 @default.
• W2137665534 cites W4251966800 @default.
• W2137665534 cites W4254177903 @default.
• W2137665534 doi "https://doi.org/10.1093/jme/tjv078" @default.
• W2137665534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26336218" @default.
• W2137665534 hasPublicationYear "2015" @default.
• W2137665534 type Work @default.
• W2137665534 sameAs 2137665534 @default.
• W2137665534 citedByCount "13" @default.
• W2137665534 countsByYear W21376655342016 @default.
• W2137665534 countsByYear W21376655342017 @default.
• W2137665534 countsByYear W21376655342018 @default.
• W2137665534 countsByYear W21376655342020 @default.
• W2137665534 countsByYear W21376655342021 @default.
• W2137665534 countsByYear W21376655342022 @default.
• W2137665534 countsByYear W21376655342023 @default.
• W2137665534 crossrefType "journal-article" @default.
• W2137665534 hasAuthorship W2137665534A5003350180 @default.
• W2137665534 hasAuthorship W2137665534A5005121219 @default.
• W2137665534 hasAuthorship W2137665534A5009994811 @default.
• W2137665534 hasAuthorship W2137665534A5010143613 @default.
• W2137665534 hasAuthorship W2137665534A5012679226 @default.
• W2137665534 hasBestOaLocation W21376655342 @default.
• W2137665534 hasConcept C104317684 @default.
• W2137665534 hasConcept C112418997 @default.
• W2137665534 hasConcept C136764020 @default.
• W2137665534 hasConcept C144024400 @default.
• W2137665534 hasConcept C149923435 @default.
• W2137665534 hasConcept C159047783 @default.
• W2137665534 hasConcept C161176658 @default.
• W2137665534 hasConcept C18903297 @default.
• W2137665534 hasConcept C2776035571 @default.
• W2137665534 hasConcept C2776468184 @default.
• W2137665534 hasConcept C2777553912 @default.
• W2137665534 hasConcept C2777625466 @default.
• W2137665534 hasConcept C2778554237 @default.
• W2137665534 hasConcept C2778908745 @default.
• W2137665534 hasConcept C2779881037 @default.
• W2137665534 hasConcept C2780394580 @default.
• W2137665534 hasConcept C2908647359 @default.
• W2137665534 hasConcept C33070731 @default.
• W2137665534 hasConcept C40767141 @default.
• W2137665534 hasConcept C41008148 @default.
• W2137665534 hasConcept C42972112 @default.
• W2137665534 hasConcept C54355233 @default.
• W2137665534 hasConcept C71924100 @default.
• W2137665534 hasConcept C71928629 @default.
• W2137665534 hasConcept C86803240 @default.
• W2137665534 hasConcept C90856448 @default.
• W2137665534 hasConcept C92087593 @default.
• W2137665534 hasConceptScore W2137665534C104317684 @default.
• W2137665534 hasConceptScore W2137665534C112418997 @default.
• W2137665534 hasConceptScore W2137665534C136764020 @default.
• W2137665534 hasConceptScore W2137665534C144024400 @default.
• W2137665534 hasConceptScore W2137665534C149923435 @default.
• W2137665534 hasConceptScore W2137665534C159047783 @default.
• W2137665534 hasConceptScore W2137665534C161176658 @default.
• W2137665534 hasConceptScore W2137665534C18903297 @default.
• W2137665534 hasConceptScore W2137665534C2776035571 @default.
• W2137665534 hasConceptScore W2137665534C2776468184 @default.
• W2137665534 hasConceptScore W2137665534C2777553912 @default.
• W2137665534 hasConceptScore W2137665534C2777625466 @default.
• W2137665534 hasConceptScore W2137665534C2778554237 @default.
• W2137665534 hasConceptScore W2137665534C2778908745 @default.
• W2137665534 hasConceptScore W2137665534C2779881037 @default.
• W2137665534 hasConceptScore W2137665534C2780394580 @default.
• W2137665534 hasConceptScore W2137665534C2908647359 @default.
• W2137665534 hasConceptScore W2137665534C33070731 @default.
• W2137665534 hasConceptScore W2137665534C40767141 @default.
• W2137665534 hasConceptScore W2137665534C41008148 @default.
• W2137665534 hasConceptScore W2137665534C42972112 @default.
• W2137665534 hasConceptScore W2137665534C54355233 @default.
• W2137665534 hasConceptScore W2137665534C71924100 @default.
• W2137665534 hasConceptScore W2137665534C71928629 @default.

• next