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- W2137813262 abstract "Chemokines constitute a large family of chemotactic cytokines that act at G protein-coupled receptors to regulate diverse biological processes, including leukocyte trafficking, angiogenesis, hematopoiesis, and organogenesis. They are believed to be both beneficial in host defense against infectious agents and harmful in diseases marked by pathologic inflammation; however, actual clinical roles in these areas have not yet been established. Recently, unexpected ways have been discovered in which medically important pathogens, including HIV-1, exploit or subvert the chemokine system. These and other recent results suggest that targeting specific chemokines and chemokine receptors may have therapeutic utility in both inflammation and infectious disease." @default.
- W2137813262 created "2016-06-24" @default.
- W2137813262 creator A5018870571 @default.
- W2137813262 creator A5068107996 @default.
- W2137813262 date "1999-02-01" @default.
- W2137813262 modified "2023-10-14" @default.
- W2137813262 title "Chemokines and Chemokine Receptors: Biology and Clinical Relevance in Inflammation and AIDS" @default.
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- W2137813262 doi "https://doi.org/10.1146/annurev.med.50.1.425" @default.
- W2137813262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10073287" @default.
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